“…FMOs have been demonstrated to utilize oxygen and nicotinamide adenine dinucleotide phosphate (NADPH) to oxidize xenobiotics containing a ‘soft nucleophile’, usually nitrogen or sulphur (Eswaramoorthy et al ., ). The mammalian FMOs, including human (Schlenk et al ., ; Cashman & Zhang, ; Motika et al ., ), mouse (Dixit & Roche, ; Zhang et al ., ; Siddens et al ., )), rabbit (Burnett et al ., ; Larsen‐Su et al ., ), dog (Lattard et al ., ) and camel (Raza et al ., ), etc., play significant roles in drug metabolism including pesticides, such as phorate, disulfoton, fenthion, fonofos, methiocarb and carbaryl (Hodgson & Levi, ; Buronfosse et al ., ; Henderson et al ., ; Leoni et al ., ; Fujino et al ., ). Insecticide metabolism by FMOs has also been observed in nonmammals.…”