Developmental Pathways of the Family Bereavement Program to Prevent Major Depression 15 Years Later

Sandler, Irwin N.; Tein, Jenn-Yun; Zhang, Na; Wolchik, Sharlene A.

doi:10.1016/j.jaac.2023.02.012

Cited by 10 publications

(4 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regardless of the limitations, the present study provides an important contribution to the literature on the cascading effects of a preventive family-based intervention for parentally bereaved youth on postloss growth outcomes 15 years later. The findings underscore the efficacy of a preventive, parenting-focused intervention in generating stronger parent-child bonds and the mediating pathways in which the intervention can have "cross-over" promotive effects on long-term postloss growth outcomes as well as previously demonstrated effects to reduce problem outcomes Sandler et al, 2023). While the understandable negative aspects of parental loss in childhood have been well documented and continue to be examined in the literature, our findings align with a strength-based approach and suggest that program effects to improve quality of parenting not only reduces problem outcomes but also boosts postloss growth in parentally bereaved youth.…”

Section: Discussionmentioning

confidence: 62%

“…Our cascade model focused on the quality of parenting as the first mediator immediately after the intervention because parenting has been found to mediate many of the effects of the FBP in prior studies (Sandler et al, 2023;Tein et al, 2006;Zhang et al, 2023) and because the Kilmer et al (2014) conceptual model proposed that positive parent-child relationships can promote postloss growth in children. Indeed, others' work consistently emphasized the key influence of caregivers on children's outcomes after parental death (Alvis et al, 2023;Jiao et al, 2021).…”

Section: The Present Studymentioning

confidence: 99%

See 1 more Smart Citation

Developmental pathways of the family bereavement program to promote growth 15 years after parental death.

Fritzson,

Zhang,

Wolchik

et al. 2024

Journal of Family Psychology

Self Cite

View full text Add to dashboard Cite

Although parental death increases the risks of negative developmental outcomes, some individuals report personal growth, an outcome that has received little attention. We tested a developmental cascade model of postloss growth in 244 parentally bereaved youth (ages 8-16 at baseline) from 156 families who participated in a randomized controlled trial of a family-based intervention, the Family Bereavement Program (FBP). Using five waves of data, the present study examined the prospective associations between the quality of parenting immediately following the FBP and postloss growth 6 and 15 years later, and whether these associations were mediated by changes in intra-and interpersonal factors (mediators) during the initial 11 months following the FBP. The mediators were selected based on the theoretical and empirical literature on postloss growth in youth. Results showed that improved quality of parenting immediately following the FBP was associated with increased support-seeking behaviors and higher perceived parental warmth at the 11-month follow-up, both of which were related to postloss growth at the 6-year follow-up and 15-year follow-up. No support was found for the other hypothesized mediators that were tested: internalizing problems, intrusive grief thoughts, and coping efficacy. To promote postloss growth for parentally bereaved youth, bereavement services should target parent-child relationships that help youth feel a sense of parental warmth and acceptance and encourage youth to seek parental support.

show abstract

Section: Discussionmentioning

confidence: 62%

Section: The Present Studymentioning

confidence: 99%

Developmental pathways of the family bereavement program to promote growth 15 years after parental death.

Fritzson,

Zhang,

Wolchik

et al. 2024

Journal of Family Psychology

Self Cite

View full text Add to dashboard Cite

show abstract

“…These findings extend the breadth of long-term program effects of the FBP. Prior studies have found that the program has long-term effects in emerging/young adulthood to reduce G2 major depression, generalized anxiety disorder, internalizing problems, externalizing problems, suicide thoughts/attempts, and use of mental health services and psychiatric medication Sandler et al, 2016b, 2018, 2023). The current study identified pathways through which the FBP may have effects that are transmitted to subsequent generations.…”

Section: Discussionmentioning

confidence: 99%

Effects of a preventive parenting intervention for bereaved families on the intergenerational transmission of parenting attitudes: Mediating processes

et al. 2023

Self Cite

View full text Add to dashboard Cite

This study evaluated whether the Family Bereavement Program (FBP), a prevention program for parentally bereaved families, improved parenting attitudes toward parental warmth and physical punishment in young adult offspring 15 years after participation and identified mediational cascade pathways. One hundred fifty-six parents and their 244 offspring participated. Data were collected at pretest (ages 8–16), posttest, and six- and 15-year follow-ups. Ethnicity of offspring was: 67% non-Hispanic Caucasian, 16% Hispanic, 7% African American, 3% Native American, 1% Asian or Pacific Islander, and 6% other; 54% were males. There was a direct effect of the FBP on attitudes toward physical punishment; offspring in the FBP had less favorable attitudes toward physical punishment. There were also indirect effects of the FBP on parenting attitudes. The results supported a cascade effects model in which intervention-induced improvements in parental warmth led to fewer externalizing problems in adolescence/emerging adulthood, which in turn led to less favorable attitudes toward physical punishment. In addition, intervention-induced improvements in parental warmth led to improvements in anxious romantic attachment in mid-to-late adolescence/emerging adulthood, which led to more favorable attitudes toward parental warmth in emerging/young adulthood. These findings suggest that the effects of relatively brief prevention programs may persist into subsequent generations.

show abstract

“…Depression, a common psychiatric disorder characterized by low mood and aversion to activity, is among the leading causes of disability worldwide. [ 1 ] The main hypotheses surrounding the pathophysiology of depression include brain monoamine receptor dysfunction, reduced monoamine secretion, general monoamine system impairment, and secondary messenger system dysfunction. [ 2,3,4 ] Despite treatment with a broad range of antidepressants, less than half of all patients with depression respond adequately to drug therapies.…”

Section: Introductionmentioning

confidence: 99%

Brain‐Targeted Black Phosphorus‐Based Nanotherapeutic Platform for Enhanced Hypericin Delivery in Depression

Tan,

Cao,

Zhao

et al. 2024

Small

View full text Add to dashboard Cite

Depression is a significant global health concern that remains inadequately treated due to the limited effectiveness of conventional drug therapies. One potential therapeutic agent, hypericin (HYP), is identified as an effective natural antidepressant. However, its poor water solubility, low bioavailability, and limited ability to penetrate the brain parenchyma have hindered its clinical application. To address these shortcomings and enhance the therapeutic efficacy of HYP, it is loaded onto black phosphorus nanosheets (BP) modified with the neural cell‐targeting peptide RVG29 to synthesize a nanoplatform named BP‐RVG29@HYP (BRH). This platform served as a nanocarrier for HYP and integrated the advantages of BP with advanced delivery methods and precise targeting strategies. Under the influence of 808 nm near‐infrared irradiation (NIR), BRH effectively traversed an in vitro BBB model. In vivo experiments validated these findings, demonstrating that treatment with BRH significantly alleviated depressive‐like behaviors and oxidative stress in mice. Importantly, BRH exhibited an excellent safety profile, causing minimal adverse effects, which highlighted its potential as a promising therapeutic agent. In brief, this novel nanocarrier holds great promise in the development of antidepressant drugs and can create new avenues for the treatment of depression.

show abstract

Developmental Pathways of the Family Bereavement Program to Prevent Major Depression 15 Years Later

Cited by 10 publications

References 39 publications

Developmental pathways of the family bereavement program to promote growth 15 years after parental death.

Developmental pathways of the family bereavement program to promote growth 15 years after parental death.

Effects of a preventive parenting intervention for bereaved families on the intergenerational transmission of parenting attitudes: Mediating processes

Brain‐Targeted Black Phosphorus‐Based Nanotherapeutic Platform for Enhanced Hypericin Delivery in Depression

Contact Info

Product

Resources

About