Pediatric Orthopedic Deformities, Volume 2 2019
DOI: 10.1007/978-3-030-02021-7_5
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Developmental Disorders of the Knee

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(13 citation statements)
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“…7 The ossification within the distal femur is the first secondary ossification center to appear in the immature skeleton, at around week 33 of gestation, followed by the ossification within the proximal tibia, and both are visible on radiographs by birth in full-term infants. 5 In contrast, the patella and the tibial tuberosity ossifications are not visible at birth. The patella ossification is visible at a median age of 3.3 years in girls and 4.7 years in boys.…”
Section: Endochondral Ossificationmentioning
confidence: 99%
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“…7 The ossification within the distal femur is the first secondary ossification center to appear in the immature skeleton, at around week 33 of gestation, followed by the ossification within the proximal tibia, and both are visible on radiographs by birth in full-term infants. 5 In contrast, the patella and the tibial tuberosity ossifications are not visible at birth. The patella ossification is visible at a median age of 3.3 years in girls and 4.7 years in boys.…”
Section: Endochondral Ossificationmentioning
confidence: 99%
“…By week 10 of gestation, the knee joint resembles that of an adult knee. 4,5 In the future long bones, such as the femur and the tibia, this process begins within the midshaft of the cartilaginous model (future diaphysis) where chondrocyte hypertrophy and matrix calcification immediately precede the appearance of the primary ossification center. Localized vascular invasion brings osteoblastic and osteoclastic precursors, responsible for producing osteoid on the calcified matrix and osseous remodeling to generate the future medullary cavity, respectively.…”
Section: Development and Maturationmentioning
confidence: 99%
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