Developmental disorders Journal Meeting: a collaboration between Development and Disease Models & Mechanisms

Abstract

Developmental disorders present at birth or arise during childhood, leading to physical or intellectual disabilities with long-term effects on morbidity. According to a study from the Centers for Disease Control and Prevention, one in six children in the USA has a developmental disability that affects their education and lifestyle (Zablotsky et al., 2019). These disorders encompass a wide range of conditions, and are caused by genetic and/or environmental factors. Expanding research in this area is fundamental to improving diagnosis, preventing progression and treating these conditions. At Disease Models & Mechanisms (DMM), we have a strong interest in research that delineates the mechanisms that underlie developmental disorders, with a dedicated collection of Reviews, Perspectives and Research articles. We pursue pre-clinical modelling to discover new mechanistic insights with a view towards how this can support children and their families, and inform their care.