Developmental differences in the neural bases of the face inversion effect show progressive tuning of face-selective regions to the upright orientation

Passarotti, Alessandra M.; Smith, Jeremy L; DeLano, Mark C.; Huang, Jie

doi:10.1016/j.neuroimage.2006.07.045

Cited by 85 publications

(75 citation statements)

References 73 publications

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“…In the age range of this sample, the brain undergoes system-wide changes, including extensive myelination and synaptic pruning (Lenroot and Giedd 2006;Paus et al 1999;Taylor 2006), consistent with our finding that activity from almost all areas of the brain became less predictable with increased age. The increased variability suggests a dynamical system with a broad functional scope and a multitude of metastable states (Ghosh et al 2008).…”

Section: Developmentsupporting

confidence: 89%

“…Similar reversals have been reported in the fMRI literature as well. In children, the BOLD inversion effect is sometimes reversed and in adolescents it is not statistically significant (Passarotti et al 2007). We conjecture that the reversals in the inversion effect may reflect an interaction between the distinct rates of development of holistic and configural processing .…”

Section: Face Inversion and Developmentmentioning

confidence: 77%

“…1) while children (6 -16 yr) and adults performed a face recognition task with upright and upside-down (inverted) faces. We hypothesized that age-dependent increases in variability should be observed across most of the brain, because in the age range of our sample, almost all cortical areas are subject to some degree of myelination and synaptic pruning (Lenroot and Giedd 2006;Paus et al 1999). However, if the variability of regional signals reflects their participation in emerging structural and functional networks, the greatest age-dependent increases should be observed in areas that are highly interconnected with the rest of the cortex and that occupy central positions (Hagmann et al 2008) in multiple such networks.…”

Section: Introductionmentioning

confidence: 99%

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Brain Noise Is Task Dependent and Region Specific

Mišić

Mills

Taylor

et al. 2010

Journal of Neurophysiology

143

102

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. The emerging organization of anatomical and functional connections during human brain development is thought to facilitate global integration of information. Recent empirical and computational studies have shown that this enhanced capacity for information processing enables a diversified dynamic repertoire that manifests in neural activity as irregularity and noise. However, transient functional networks unfold over multiple time, scales and the embedding of a particular region depends not only on development, but also on the manner in which sensory and cognitive systems are engaged. Here we show that noise is a facet of neural activity that is also sensitive to the task context and is highly region specific. Children (6 -16 yr) and adults (20 -41 yr) performed a one-back face recognition task with inverted and upright faces. Neuromagnetic activity was estimated at several hundred sources in the brain by applying a beamforming technique to the magnetoencephalogram (MEG). During development, neural activity became more variable across the whole brain, with most robust increases in medial parietal regions, such as the precuneus and posterior cingulate cortex. For young children and adults, activity evoked by upright faces was more variable and noisy compared with inverted faces, and this effect was reliable only in the right fusiform gyrus. These results are consistent with the notion that upright faces engender a variety of integrative neural computations, such as the relations among facial features and their holistic constitution. This study shows that transient changes in functional integration modulated by task demand are evident in the variability of regional neural activity.

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Section: Developmentsupporting

confidence: 89%

Section: Face Inversion and Developmentmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

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Brain Noise Is Task Dependent and Region Specific

Mišić

Mills

Taylor

et al. 2010

Journal of Neurophysiology

143

102

View full text Add to dashboard Cite

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“…The activation of faceselective regions such as the FFA becomes progressively more specialized through childhood into adulthood (Golarai, Ghahremani, Whitfield-Gabrieli, Reiss, Eberhardt, Gabrieli, & GrillSpector, 2007;Joseph, Gathers, & Bhatt, 2011). Neural systems involved in adult face perception have a protracted developmental trajectory, and only become fully tuned to upright faces in early adulthood (Taylor, Batty, & Itier, 2004;Passarotti, Smith, DeLano, & Huang, 2007). The presence of N170 amplitude enhancements to inverted or scrambled faces in controls, and the absence of these effects in individuals with DP could thus be linked to a general reduction in the selectivity of face-selective visual processing to intact upright faces in DP.…”

Section: Discussionmentioning

confidence: 99%

Perceptual face processing in developmental prosopagnosia is not sensitive to the canonical location of face parts

Towler

Parketny

Eimer

2016

Cortex

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“…Functional brain imaging studies revealed enhanced dorsal visual stream activity in adults compared to children related to motion defined visual perception as well as visuospatial memory and attention Klingberg, 2006;. By contrast object recognition related activity in the ventral stream showed reduced activity related to unspecific object categories (Cantlon et al, 2011;Golarai et al, 2007;Klaver et al, 2008;Lichtensteiger et al, 2008;Passarotti, Smith, DeLano, & Huang, 2007;Peelen et al, 2009). It was suggested that neural tuning may increase neural specificity towards specialized object categories in the ventral stream (Grill-Spector, Golarai, & Gabrieli, 2008), whereas dorsal stream enhancement may reflect consolidation mediated specialization .…”

mentioning

confidence: 99%

Occipital cortical thickness in very low birth weight born adolescents predicts altered neural specialization of visual semantic category related neural networks

2015

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Very low birth weight (VLBW) premature born infants have a high risk to develop visual perceptual and learning deficits as well as widespread functional and structural brain abnormalities during infancy and childhood. Whether and how prematurity alters neural specialization within visual neural networks is still unknown. We used functional and structural brain imaging to examine the visual semantic system of VLBW born (<1250 g, gestational age 25-32 weeks) adolescents (13-15 years, n=11, 3 males) and matched term born control participants (13-15 years, n=11, 3 males). Neurocognitive assessment revealed no group differences except for lower scores on an adaptive visuomotor integration test. All adolescents were scanned while viewing pictures of animals and tools and scrambled versions of these pictures. Both groups demonstrated animal and tool category related neural networks. Term born adolescents showed tool category related neural activity, i.e. tool pictures elicited more activity than animal pictures, in temporal and parietal brain areas. Animal category related activity was found in the occipital, temporal and frontal cortex. VLBW born adolescents showed reduced tool category related activity in the dorsal visual stream compared with controls, specifically the left anterior intraparietal sulcus, and enhanced animal category related activity in the left middle occipital gyrus and right lingual gyrus. Lower birth weight of VLBW adolescents correlated with larger thickness of the pericalcarine gyrus in the occipital cortex and smaller surface area of the superior temporal gyrus in the lateral temporal cortex. Moreover, larger thickness of the pericalcarine gyrus and smaller surface area of the superior temporal gyrus correlated with reduced tool category related activity in the parietal cortex. Together, our data suggest that very low birth weight predicts alterations of higher order visual semantic networks, particularly in the dorsal stream. The differences in neural specialization may be associated with aberrant cortical development of areas in the visual system that develop early in childhood. DOI: https://doi.org/10.1016/j.neuropsychologia. 2014.10.030 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-102927 Accepted VersionOriginally published at: Klaver, Peter; Latal, Beatrice; Martin, Ernst (2015). Occipital cortical thickness in very low birth weight born adolescents predicts altered neural specialization of visual semantic category related neural networks. Neuropsychologia, This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the j...

show abstract

Developmental differences in the neural bases of the face inversion effect show progressive tuning of face-selective regions to the upright orientation

Cited by 85 publications

References 73 publications

Brain Noise Is Task Dependent and Region Specific

Brain Noise Is Task Dependent and Region Specific

Perceptual face processing in developmental prosopagnosia is not sensitive to the canonical location of face parts

Occipital cortical thickness in very low birth weight born adolescents predicts altered neural specialization of visual semantic category related neural networks

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