Developmental basis of the portal venous system

Microanatomy of the human liver?exploring the hidden interfaces

“…In fetal life, organization of the hepatic epithelial cords occurs around the developing PV, which itself arises from the vitelline and umbilical veins; the HA playing an insignificant role in this process. 44 On the other hand, the development of the HA closely parallels the development of the BDs in both rats and humans. 45,46 In both species, the arterial system, just like the biliary system, is immature at birth.…”

Stepwise management of hepatocellular carcinoma associated with Abernethy syndrome

“…Excessive involution of this loop can cause congenital agenesis of the portal vein, with the development of a complete or partial mesocaval shunt, as reported here 3, 4.…”

Polysplenia Syndrome with Various Visceral Anomalies in an Adult: Embryological and Clinical Considerations.

“…There have been only 7 case reports of PPV in polysplenia syndrome (9,(14)(15)(16)(17)(18)(19). The embryogenesis of PPV is well described by Marks (20). The occurrence of PPV may not simply result from the maldevelopment of the portal venous system itself because PPV is frequently found in combination with various congenital anomalies including intestinal malrota tion, situs inversus, duodenal atresia, annular pancreas, biliary atresia and splenic anomalies (21).…”