Developmental antecedents of anxiety sensitivity

Scher, Christine D.; Stein, Murray B.

doi:10.1016/s0887-6185(02)00202-5

Cited by 61 publications

(52 citation statements)

References 27 publications

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“…One study has examined the relationship between parental behaviors and child AS [36], reporting that childhood exposure to parental behaviors classified as threatening, hostile, and rejecting was significantly predictive of later AS. Specifically, Scher and Stein [36] reported that parental rejection/aggression/hostility scores accounted for 6.7% of variance in offspring AS.…”

Section: Parental Cognitions and Behaviors As Predictors Of Child Asmentioning

confidence: 99%

“…Specifically, Scher and Stein [36] reported that parental rejection/aggression/hostility scores accounted for 6.7% of variance in offspring AS. Of the three parental behaviors examined, parental threatening behavior best predicted child AS, accounting for 6.6% of its variance and remaining a significant predictor of child AS when parental hostility and rejection were controlled for.…”

Section: Parental Cognitions and Behaviors As Predictors Of Child Asmentioning

confidence: 99%

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Parental Contributions to Child Anxiety Sensitivity: A Review and Recommendations for Future Directions

Francis

Noël

2010

Child Psychiatry Hum Dev

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Anxiety sensitivity (AS) is defined as the fear of anxiety-related symptoms (e.g., a fast beating heart) and the consequences that may follow from these symptoms (e.g., a heart attack). Recently, child AS has been examined in relation to parental AS and parental anxiety to elucidate potential parental contributions. Given inconsistent findings to date, this review was intended to identify parental factors that are significant contributors to child AS. Two key findings from this review included the absence of a significant relationship between parental anxiety and child AS and the determination that the parent-child AS association is conditional upon the child reporter, the parent reporter, and the specific dimensions of AS being tested. Recommendations for future directions include examining specific facets of AS, studying parental contributions amongst anxiety-disordered youth, and employing sufficiently large samples to allow for between child group comparisons.

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Section: Parental Cognitions and Behaviors As Predictors Of Child Asmentioning

confidence: 99%

Section: Parental Cognitions and Behaviors As Predictors Of Child Asmentioning

confidence: 99%

Parental Contributions to Child Anxiety Sensitivity: A Review and Recommendations for Future Directions

Francis

Noël

2010

Child Psychiatry Hum Dev

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“…Hazen et al (1996), in a study with adults, found that anxiety sensitivity could be lowered using cognitive behavioral methods such as providing psychoeducation about anxiety, cognitive restructuring, and introceptive exposures and in-vivo exposures. In addition, several studies found parental behaviors such as parent hostility, threats, rejecting behaviors, and parental reinforcement of sick-role behavior in their children played a contributory role in the development of anxiety sensitivity (Cohan et al 2004;Scher and Stein 2003;Watt et al 1998). This information is not to be used to blame parents, but suggests potential avenues for intervention with parents exhibiting these behaviors, while co-jointly treating the child.…”

Section: Anxiety Sensitivitymentioning

confidence: 99%

Cognitive Risk Factors to the Development of Anxiety and Depressive Disorders in Adolescents

Dia

Bradshaw

2008

Child Adolesc Soc Work J

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This exploratory study examines cognitive risk factors, anxiety sensitivity, and positive and negative affect, as related to the development of anxiety and depression. In a mailed survey, adolescents completed the Child Anxiety Sensitivity Index and the Positive and Negative Affectivity Scale. Previous research utilized the broad and unified variable of anxiety sensitivity as a predictor of anxiety. In this study, we separate and examine the four specific factors of anxiety sensitivity: mental incapacitation concerns, social concerns, disease concerns, and unsteady concerns, and relate it to specific anxiety disorders and depression. Results indicate good convergent validity and improved divergent validity when utilizing the four factors of anxiety sensitivity as compared to using it as one construct. Results also suggest: (1) OCD and GAD share numerous similarities and (2) the importance of the role of negative affectivity in anxiety and depression. Being aware of the components of anxiety sensitivity and how they relate to specific anxiety disorders can help a social worker when rendering a diagnosis.A review of the literature establishes that anxiety and depression are common in adolescents with a 12-month prevalence rate of 6.9% for anxiety and 1.7% for depression (Roberts et al. 2006). These disorders can develop during childhood or later in adolescence and can potentially create a significant burden for the

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“…Twin research has shown that variation in AS (particularly the physical concerns aspect of AS) is explained by unique (as opposed to shared) environmental and additive genetic influences (Stein et al, 1999). Emotional maltreatment in childhoodFparticularly when it includes parental threatening, hostile, and rejecting behaviorsFis associated with higher levels of AS in young adults (Scher and Stein, 2003). Thus, childhood emotional maltreatment is a plausible candidate to be an environmental risk factor for AS.…”

Section: Introductionmentioning

confidence: 99%

Gene-by-Environment (Serotonin Transporter and Childhood Maltreatment) Interaction for Anxiety Sensitivity, an Intermediate Phenotype for Anxiety Disorders

Stein

Schork

Gelernter

2007

Neuropsychopharmacol

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204

146

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Anxiety sensitivity (AS) is a dispositional characteristic that predisposes to the development of anxiety disorders (eg, panic and posttraumatic stress disorder) and major depression. AS is subject to genetic and environmental influences, the former as yet unidentified and the latter known to include childhood maltreatment. The serotonin transporter gene (SLC6A4) promoter polymorphism (5-HTTLPR) has been associated with depression, but most consistently in the context of environmental stress. We tested the hypothesis that 5-HTTLPR genotype and childhood maltreatment would interact to increase susceptibility to AS in young adults. Subjects were European-American college undergraduates (N ¼ 150, median age 18 years) characterized on a measures of AS (Anxiety Sensitivity Index) and retrospective childhood maltreatment (Childhood Trauma Questionnaire [CTQ]). 5-HTTLPR genotypes were obtained from blood-derived DNA. Linear regression was used to model relationships between 5-HTTLPR, childhood emotional abuse, and AS; covariates such as sex, neuroticism, and ancestral proportion scores were incorporated into some models in a larger, ethnically heterogenous sample (N ¼ 247) to evaluate robustness of the findings to model assumptions. A statistically signficant interaction was observed between levels of childhood emotional (or physical) maltreatment and 5-HTTLPR genotype. Specifically, S/S individuals with higher levels of maltreatment had significantly higher levels of AS than subjects in other groups. No such relationship was found for neuroticism, attesting to the possible specificity of the findings for AS. Findings were consistently robust to the inclusion of covariates, and were not confounded by population stratification. In conclusion, these results provide evidence of a specific genetic influence on anxiety sensitivityFan intermediate phenotype for anxiety (and depressive) disorders; this effect is modified by severity of childhood maltreatment. These findings are consistent with the notion that 5-HTTLPR operates broadly to moderate emotional responsivity to stress.

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Developmental antecedents of anxiety sensitivity

Cited by 61 publications

References 27 publications

Parental Contributions to Child Anxiety Sensitivity: A Review and Recommendations for Future Directions

Parental Contributions to Child Anxiety Sensitivity: A Review and Recommendations for Future Directions

Cognitive Risk Factors to the Development of Anxiety and Depressive Disorders in Adolescents

Gene-by-Environment (Serotonin Transporter and Childhood Maltreatment) Interaction for Anxiety Sensitivity, an Intermediate Phenotype for Anxiety Disorders

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