Developmental and Behavioral Disorders Grown Up: Tourette's Disorder

Zinner, Samuel H.; Coffey, Barbara J.

doi:10.1097/dbp.0b013e3181bd7f3e

Cited by 14 publications

(13 citation statements)

References 111 publications

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“…12–16 Additionally, chronic tic disorders and ASD have many common features, including stereotyped repetitive behaviors that are aggravated or worsened by heightened emotional states (tics and stereotypies), and higher prevalence in males than females. 17 However, the presence and profile of autism spectrum symptoms in individuals affected with TS has not been systematically assessed in a large sample.…”

Section: Introductionmentioning

confidence: 99%

Autism Spectrum Symptoms in a Tourette’s Disorder Sample

Darrow

Grados

Sandor

et al. 2017

Journal of the American Academy of Child & Adolescent Psych

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Objective Tourette syndrome (TS) and autism spectrum disorder (ASD) share clinical features and possibly an overlapping etiology. This study: 1) examined ASD symptom rates in participants with TS and 2) characterized the relationships between ASD symptom patterns and TS, obsessive-compulsive disorder (OCD), and attention-deficit/hyperactivity disorder (ADHD). Method Participants with TS (n = 535) and their family members (n =234) recruited for genetic studies reported TS, OCD, and ADHD symptoms and completed the Social Responsiveness Scale Second Edition (SRS), which was used to characterize ASD symptoms. Results SRS scores in participants with TS were similar to those observed in other clinical samples but lower than in ASD samples (mean SRS total raw score = 51; SD=32.4). More children with TS met cut-off criteria for ASD (22.8%) than adults with TS (8.7%). The elevated rate in children was primarily due to high scores on the SRS Repetitive and Restricted Behaviors (RRB) subscale. Total SRS scores were correlated with TS (r=0.27), OCD (r=0.37), and ADHD (r=0.44) and were higher among individuals with OCD symptom-based phenotypes than for those with tics alone. Conclusion Higher observed rates of ASD among children affected by TS may in part be due to difficulty in discriminating complex tics and OCD symptoms from ASD symptoms. Careful examination of ASD-specific symptom patterns (social communication vs. repetitive behaviors) is essential. Independent of ASD, the SRS may be a useful tool for identifying patients with TS with impairments in social communication, potentially putting them at risk for bullying and other negative sequelae.

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Section: Introductionmentioning

confidence: 99%

Autism Spectrum Symptoms in a Tourette’s Disorder Sample

Darrow

Grados

Sandor

et al. 2017

Journal of the American Academy of Child & Adolescent Psych

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“…As self‐mutilation is a known co‐morbid feature of TS and from the findings in this study, we would recommend that a diagnosis of TS should be considered and evaluated in patients presenting with dental or oral self‐mutilation. In relation to TS patients, the dentist could be a relevant professional to include in the interdisciplinary diagnostic team.…”

Section: Discussionmentioning

confidence: 86%

“…It is defined by multiple motor tics and one or more phonic tics, not necessarily occurring concomitantly, but lasting for more than 1 year and with a debut before 18 years of age. Tics manifest as sudden, rapid, recurrent, non‐rhythmic, stereotyped movements, or sounds . Tics usually have a waxing and waning course.…”

Section: Introductionmentioning

confidence: 99%

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Tourette syndrome and procedures related to dental treatment: a systematic review

Hansen

Jacobsen

Simonsen

et al. 2014

Special Care in Dentistry

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“…У пациентов с СТ всех возрастных групп тики усиливаются под влиянием стрессов. Высокий уровень тревожности при СТ может быть результатом из-быточного реагирования в ответ на физиологическое вы-свобождение гормонов во время стресса [36].…”

Section: вид тиковunclassified

Chronic tics and Tourette syndrome in children and adolescents: diagnostic and treatment characteristics

Zavadenko

Доронина

Nesterovsky

2015

Z. nevrol. psikhiatr. im. S.S. Korsakova

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ЛЕКЦИЯТики -внезапные, быстрые, повторяющиеся, нерит-мичные моторные движения или вокализации [1]. По со-временным критериям Международной классификации болезней 10-го пересмотра (МКБ-10) [2,3], классифика-ции Американской психиатрической ассоциации DSM-V [1] и исследовательской группы по классификации син-дрома Туретта (СТ) [4,5] определяются следующие фор-мы первичных тикозных расстройств: транзиторное ти-козное расстройство (тики длятся не менее 4 нед, но не более 12 мес), хронические тики (ХТ) продолжительно-стью более одного года, СТ (комбинированное голосовое и множественное двигательное тикозное расстройство).Дебют тикозных расстройств в большинстве случаев приходится на возраст от 2 до 15 лет. Часто они диагности-руются поздно или не диагностируются совсем, поэтому многие пациенты не получают адекватной помощи и в те- Хронические тики (ХТ) встречаются у 3-4% населения, синдром Туретта (СТ) -у 0,1-3,0%. Дебют тикозных расстройств в большинстве случаев приходится на возраст от 2 до 15 лет. но они часто диагностируются поздно. Клинические проявления тиков и сопутствующих им расстройств разнообразны и зависят от возраста ребенка. Трудности в лечении ХТ связаны с их персистированием, СТ -с флюктуирующим течением тиков, а также возможным дебютом заболевания поведенческих нарушений. Лечение ХТ и СТ носит индивидуальный характер: если тики не мешают пациентам в их повседневной жизни, то на определенный период могут рекомендоваться методы поведенческой и психотерапии; усиление и учащение тиков служат показаниями для назначения фармакотерапевтических средств. Рассматриваются Европейские рекомендации по фармакотерапии тикозных расстройств и доступные в России препараты. Приводятся данные исследований эффективности при ХТ и СТ противоэпилептических препаратов, а также препарата тенотен детский. Ключевые слова: хронические тики, синдром Туретта, диагноз, комордидные расстройства, фармакотерапия, тенотен детский.Chronic tics (CT) are observed in 34% population, Tourette syndrome (TS) in 0.1-3.0%. In most cases, tic disorders start at age 2-15 years, but frequently they are diagnosed late. Clinical presentations of tics and comorbid disorders are various and depend on child's age. Difficulties in treatment of CT are associated with their persistence and those for TS with the fluctuating course of tics and probable onset of the disease in the form of behavioral disorders. Treatment of CT and TS is individual. Methods of behavioral and psychotherapy are recommended for a certain period of time if tics do not hamper everyday life. Increase in tick frequency and severity indicate the necessity of using pharmacological treatment. The European recommendations on pharmacotherapy of tic disorders and the drugs available in Russia are considered. Results of the studies on the efficacy of antiepileptic drugs and tenoten children in CT and TS are presented.Key words: chronic tics, Tourette syndrome, diagnosis, comorbid disorders, pharmacotherapy, tenoten children. чение длительного времени страдают не только от самого заболева...

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Developmental and Behavioral Disorders Grown Up: Tourette's Disorder

Cited by 14 publications

References 111 publications

Autism Spectrum Symptoms in a Tourette’s Disorder Sample

Autism Spectrum Symptoms in a Tourette’s Disorder Sample

Tourette syndrome and procedures related to dental treatment: a systematic review

Chronic tics and Tourette syndrome in children and adolescents: diagnostic and treatment characteristics

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