To explore the role of Marangoni effects in the pool boiling heat transfer of binary mixtures, experiments have been conducted with water/2-propanol mixtures at three different concentrations under normal gravity with different orientations of the heater surface. The system pressure was subatmospheric (∼5.5 kPa) and the bulk liquid temperature was near the saturation temperature of the fluids tested. The molar concentrations of2-propanol tested were 0.015, 0.025, and 0.1. These concentrations of 2-propanol are selected because their strong variation of surface tension with concentration gives rise to high surface tension gradients near the heater surface during nucleate boiling. Boiling curves were obtained both for an upward-facing and a downward-facing heater surface. For each concentration of 2-propanol, the critical heat flux has been reached in both orientations of the heater surface. Models of pool boiling heat transfer and the critical heat flux condition for binary mixtures are tested to correlate the data. Comparison of boiling curves and CHF obtained at different orientations of the heater surface indicates that there is strong gravity independent mechanism of boiling heat transfer in these mixtures.