Abstract:The low penetration of berberine chloride (BBR) through the skin is due to its hydrophilic characteristic. Therefore, this study aims to enhance the penetration of BBR using transfersomal emulgel for transdermal delivery. Four formulations used were prepared by varying the ratio of the main ingredient concentrations and the transfersomes were also prepared by a solvent evaporation method. Subsequently, the BBR transfersomes were formulated into emulgel and in vitro penetration was carriexd out using Franz diff… Show more
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