Development of third molars in Korean juveniles and adolescents

Lee, Soo-Hyun; Lee, Jeong-Yun; Park, Heekyung; Kim, Young-Ku

doi:10.1016/j.forsciint.2009.03.033

Cited by 65 publications

(68 citation statements)

References 23 publications

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“…Another possibility is that the difference in outcomes occurred owing to difference in the studied populations. Agenesis of one or more M3 occurs with variable frequency in different human populations; the frequencies reported vary from 0.2 to 11% in Africans, 9 to 25% in Europeans and 27 to 42% in East Asians, [37][38][39][40][41][42][43] and our observation in the Korean population (31.8%) was consistent with previous studies. Moreover, M3 agenesis is associated with crown-size reduction of the extant teeth in people of European ancestry, whereas M3 agenesis is associated with large crown size of molars in Japanese.…”

Section: Discussionsupporting

confidence: 92%

Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations

et al. 2012

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Studies on the heredity of dental characteristics in humans have indicated that the variance in many dental traits results from genetic variation. However, the genetic factors that influence commonly occurring dental variants are poorly understood. Paired domain box 9 (PAX9) codes a transcription factor that is important in tooth development. We investigated whether PAX9 polymorphisms are associated with normal variations in tooth agenesis and morphology. The study subjects were 273 Japanese and 223 Korean adults. Single-nucleotide polymorphisms (SNPs) in PAX9 (rs2295222, rs4904155, rs2073244, rs12881240 and rs4904210) were genotyped, and third molar agenesis and mesiodistal and buccolingual diameters were measured. We found that four of the five SNPs were significantly associated with the crown size. However, no SNP was associated with third molar agenesis. In additional analyses on non-metric dental traits, we found significant associations of PAX9 SNPs with shoveling of upper first incisors. In summary, common variants in PAX9 contributed to morphological variation in permanent teeth in humans.

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Section: Discussionsupporting

confidence: 92%

Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations

et al. 2012

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“…Diagnostic accuracy of M3 to predict age 18 was tested. Design Methods were tested on a target sample of 300 dental panoramic radiographs (age [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Diagnostic accuracy was assessed on separate reference data (n = 1,663, age [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Estimating age and the likelihood of having attained 18 years of age using mandibular third molars

2010

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by accuracy? Do population differences in dental maturity infl uence accuracy? There is an urgent need for an evidencebased reference to address some of these questions. The fi rst aim of this study was to calculate the bias (difference between dental and real age) of age-estimating methods that use mandibular third molar (M3) root formation. The probability of being at least 18 given M3 root stage is also of interest. The second aim was to apply diagnostic tests of accuracy showing how root stage discriminates between individuals at least 18 years of age and those younger and to apply this knowledge to predict the likelihood of age 18 for a single individual. For this part of this study we used a separate reference sample of 1,663 radiographs. We propose an age interval for M3 root stages to aid interpretation of the term 'on the balance of probabilities' . We highlight the similarity in M3 apex maturity between world groups from published data and illustrate how a small group difference in average age has little impact on the confi dence interval of estimated age for an individual.

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“…It is reported by several studies that linear correlation between the development of third molar and chronological age is marked [4][5][6][7]. While our study shows that the relationship is higher in female than in male, the contrary result (r 2 in male=0.54, r 2 in female=0.45) is found by Prieto et al [8] There is high relationship (Table 5) between 18 and 28, 38 and 48 respectively, certified by other research [4,[8][9][10][11][12][13][14].…”

Section: Discussionmentioning

confidence: 99%

The Explore of Third Molar for Chronological Age Estimation in Teenagers of Shanghai Han Population

Zhu¹

2014

J Forensic

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Development of third molars in Korean juveniles and adolescents

Cited by 65 publications

References 23 publications

Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations

Association of common PAX9 variants with permanent tooth size variation in non-syndromic East Asian populations

Estimating age and the likelihood of having attained 18 years of age using mandibular third molars

The Explore of Third Molar for Chronological Age Estimation in Teenagers of Shanghai Han Population

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