Development of the posterior trunk and tail of the chick embryo

Gaertner, Robert A.

doi:10.1002/jez.1401110202

Cited by 33 publications

(7 citation statements)

References 9 publications

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“…A similar fold, called the caudal intestinal portal (CIP), arises later at the posterior end of the embryo and moves anteriorly ( Fig. 3) (Gaertner, 1949, Gasser, 1880. The two folds meet at the yolk stalk.…”

Section: Morphogenetic Events and Their Relation To A-p Patterningmentioning

confidence: 99%

Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis

Grapin-Botton¹

2005

Int. J. Dev. Biol.

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This review is dedicated to the work on chick digestive tract organogenesis that Nicole Le Douarin performed as a PhD student under the direction of Etienne Wolf. I discuss how she laid the grounds for future work by establishing fate maps at somitic stages, by describing morphogenetic movements between germ layers and by pointing to signaling events between endoderm and mesoderm. Her inspiring work was extended by others, in particular at the molecular level, leading to a better understanding of antero-posterior patterning in the digestive tract. Antero-posterior patterning of endoderm is initiated at gastrulation when future anterior and posterior endoderm ingress at different times and accordingly express different genes. Plasticity is however maintained at somite stages and even later, when organ primordia can be delineated. There is a cross-talk between endoderm and mesoderm and the two layers exchange instructive signals that induce specific antero-posterior identities as well as permissive signals required for organogenesis from previously patterned fields. Recent experiments suggest that several signaling molecules involved in neural tube antero-posterior patterning are also instrumental in the digestive tract including retinoic acid and FGF4.

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Section: Morphogenetic Events and Their Relation To A-p Patterningmentioning

confidence: 99%

Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis

Grapin-Botton¹

2005

Int. J. Dev. Biol.

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“…In the chick, as in other vertebrates, closure of the posterior neuropore ends the process known as primary body development, driven by the primitive streak. Further (secondary body) development derives from a caudal cap of tissue, the tail bud, which generates the region from the lumbosacral vertebrae to the tip of the tail (Homdahl, 1925;Gaertner, 1949;Seichart and Jelinek, 1968) (reviewed by Stern et al, 2006). The primitive streak and tail bud thus supply cells to the neural tube and mesoderm over the entire post-cranial axis (Schoenwolf, 1977;Schoenwolf, 1979a;Catala et al, 1995;Psychoyos and Stern, 1996).…”

Section: Introductionmentioning

confidence: 99%

Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity

et al. 2008

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The outgrowth of the vertebrate tail is thought to involve the proliferation of regionalised stem/progenitor cell populations formed during gastrulation. To follow these populations over extended periods, we used cells from GFP-positive transgenic chick embryos as a source for donor tissue in grafting experiments. We determined that resident progenitor cell populations are localised in the chicken tail bud. One population, which is located in the chordoneural hinge (CNH), contributes descendants to the paraxial mesoderm, notochord and neural tube, and is serially transplantable between embryos. A second population of mesodermal progenitor cells is located in a separate dorsoposterior region of the tail bud, and a corresponding population is present in the mouse tail bud. Using heterotopic transplantations, we show that the fate of CNH cells depends on their environment within the tail bud. Furthermore, we show that the anteroposterior identity of tail bud progenitor cells can be reset by heterochronic transplantation to the node region of gastrula-stage chicken embryos.

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“…1) (Kanki and Ho, 1997). Cell fates and gene expression patterns are restricted within the tailbud of chick, frog, and zebrafish embryos, indicating that tail formation is a conserved process that is not simply mediated by the addition of cells to the posterior end (Beck and Slack, 1998;Catala et al, 1995;Gaertner, 1949;Gont et al, 1993;Hammerschmidt and Nüsslein-Volhard, 1993;Joly et al, 1992;Joly et al, 1993b;Kanki and Ho, 1997;Schoenwolf, 1977;Schulte-Merker et al, 1992;Talbot et al, 1995;Tucker, 1995). However, elevated cell proliferation in dorsal medial regions might contribute to tail extension in zebrafish (Kanki and Ho, 1997).…”

Section: Introductionmentioning

confidence: 99%

No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish

et al. 2004

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The vertebrate posterior body is formed by a combination of the gastrulation movements that shape the head and anterior trunk and posterior specific cell behaviors. Here, we investigated whether genes that regulate cell movements during gastrulation [no tail(ntl)/brachyury, knypek (kny) and pipetail(ppt)/wnt5] interact to regulate posterior body morphogenesis. Both kny;ntl and ppt;ntl double mutant embryos exhibit synergistic trunk and tail shortening by early segmentation. Gene expression analysis in the compound mutants indicates that anteroposterior germ-layer patterning is largely normal and that the tail elongation defects are not due to failure to specify or maintain posterior tissues. Moreover, ntl interacts with ppt and knyto synergistically regulate the posterior expression of the gene encoding bone morphogenetic protein 4 (bmp4) but not of other known T-box genes,fibroblast growth factor genes or caudal genes. Examination of mitotic and apoptotic cells indicates that impaired tail elongation is not simply due to decreased cell proliferation or increased cell death. Cell tracing in ppt;ntl and kny;ntl mutants demonstrates that the ventral derived posterior tailbud progenitors move into the tailbud. However,gastrulation-like convergence and extension movements and cell movements within the posterior tailbud are impaired. Furthermore, subduction movements of cells into the mesendoderm are reduced in kny;ntl and ppt;ntl mutants. We propose that Ntl and the non-canonical Wnt pathway components Ppt and Kny function in parallel, partially redundant pathways to regulate posterior body development. Our work initiates the genetic dissection of posterior body morphogenesis and links genes to specific tail-forming movements. Moreover, we provide genetic evidence for the notion that tail development entails a continuation of mechanisms regulating gastrulation together with mechanisms unique to the posterior body.

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Development of the posterior trunk and tail of the chick embryo

Cited by 33 publications

References 9 publications

Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis

Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis

Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity

No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish

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