Development of the Pancreas and Related Structures

Lewis, Brian C.; Mao, Junhao

doi:10.1002/9781119188421.ch1

Cited by 3 publications

(3 citation statements)

References 44 publications

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“…The pancreas is an organ with high importance in the human and animal bodies, but one of the less studied with optical methods. The pancreas is responsible for the production of insulin in the body, which prevents the occurrence of diabetes [22]. The incidence of pancreatic cancer in humans, although rare, has been growing over past years [23].…”

Section: Introductionmentioning

confidence: 99%

Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis

et al. 2022

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The pancreas is a highly important organ, since it produces insulin and prevents the occurrence of diabetes. Although rare, pancreatic cancer is highly lethal, with a small life expectancy after being diagnosed. The pancreas is one of the organs less studied in the field of biophotonics. With the objective of acquiring information that can be used in the development of future applications to diagnose and treat pancreas diseases, the spectral optical properties of the rabbit pancreas were evaluated in a broad-spectral range, between 200 and 1000 nm. The method used to obtain such optical properties is simple, based almost on direct calculations from spectral measurements. The optical properties obtained show similar wavelength dependencies to the ones obtained for other tissues, but a further analysis on the spectral absorption coefficient showed that the pancreas tissues contain pigments, namely melanin, and lipofuscin. Using a simple calculation, it was possible to retrieve similar contents of these pigments from the absorption spectrum of the pancreas, which indicates that they accumulate in the same proportion as a result of the aging process. Such pigment accumulation was camouflaging the real contents of DNA, hemoglobin, and water, which were precisely evaluated after subtracting the pigment absorption.

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Section: Introductionmentioning

confidence: 99%

Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis

et al. 2022

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“…Pancreas is an organ that plays an important role in human and animal physiology. It is responsible for the production of insulin that prevents the occurrence of diabetes [30]. Pancreatic cancer, on the other hand, although rare, has presented an increasing number of cases over the years [31].…”

Section: Introductionmentioning

confidence: 99%

Estimation of Rabbit Pancreas Dispersion Between 400 and 1000 nm

Martins

Silva

Tuchin

et al. 2021

J-BPE

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Current biophotonics methods cover the entire optical spectrum from the deep ultraviolet to the terahertz. To optimize such methods for diagnostic and therapeutic applications, the need to obtain the wideband dispersion of tissues is high. The pancreas is a very important organ in the human body, since it produces insulin and its malfunction may induce diabetes. A reduced number of biophotonics publications regarding the pancreas is available, meaning that studies to determine its optical properties and their variation during optical clearing treatments are necessary. Considering this fact, we used the total internal reflection method to measure the refractive index of the rabbit pancreas for wavelengths between 400 and 850 nm. The experimental results allowed to calculate the pancreas dispersion with the Cauchy, Conrady and Cornu equations. It was observed that all those equations provided good data fitting in the spectral range of the measurements, but differences were observed outside these limits. Considering the wavelength of 633 nm, the mean value from the three dispersions was 1.3521, while the one published for porcine pancreas is 1.3517. The dispersion calculated with the Conrady equation does not present a fast decreasing behavior for shorter wavelengths as the ones calculated with the Cauchy and Cornu equations, but comparing these curves with a dispersion for a tissue-like material, all seem to have good agreement.

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“…Gene expression pattern of stepwise differentiation of pluripotent stem cells towards mature pancreatic β-cells, pathway in purple. Adapted from[48][49][50][51][52].…”

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confidence: 99%

Sacrificial gelatin microspheres for tissue engineering applications

Leong¹

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Development of the Pancreas and Related Structures

Cited by 3 publications

References 44 publications

Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis

Fast Estimation of the Spectral Optical Properties of Rabbit Pancreas and Pigment Content Analysis

Estimation of Rabbit Pancreas Dispersion Between 400 and 1000 nm

Sacrificial gelatin microspheres for tissue engineering applications

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