Development of the human stria vascularis

Comparisons of Auditory Steady State Response and Behavioral Air Conduction and Bone Conduction Thresholds for Infants and Adults With Normal Hearing

“…It is interesting that infant-adult differences in the occlusion effect have been observed, which suggests that transmission of bone-conducted sound may be affected by immaturities in the outer, and perhaps the middle ear (Small et al 2007;Small & Hu 2011). Rance and Tomlin (2006) and Sininger et al argue that neural immaturity, particularly in the higher frequencies, is an important source of infant-adult threshold differences because we know that the cochlea is largely mature by full-term birth, both structurally and functionally (Bredberg 1968;Pujol 1985;Lavigne-Rebillard & Pujol 1987Pujol et al 1991;Lavigne-Rebillard & Bagger-Sjöbäck 1992;Abdala 2000). Elements of the neural system that develop include myelination and synaptic transmission time (Moore et al 1995;Ponton et al 1996;Moore & Lithicum 2001), which may improve the auditory system's efficiency.…”

Developmental expression patterns of connexin26 and -30 in the rat cochlea

“…In the lateral wall of the fetal 22-week-old human cochlea staining for Cx26 was stronger as compared with Cx30. At that stage the human stria vascularis has morphologically reached an adult-like appearance [Lavigne-Rebillard and Bagger-Sjoback, 1992], but hearing begins after 30-35 weeks of gestational age [Pujol et al, 1991]. Thus in early developmental stages the expression of Cx26 is stronger than the expression of Cx30 in both humans and rats.…”

Malformation of stria vascularis in the developing inner ear of the German waltzing guinea pig

“…Stria vascularis morphogenesis has been extensively described in humans (Bibas et al 2000;Lavigne-Rebillard and Bagger-Sjöbäck 1992) and other mammals including guinea pigs (Thorn and Schinko 1985) both in vivo (Fernandez and Hinojosa 1974;Kikuchi and Hilding 1966) and in vitro (Ågrup et al 1996;Mou et al 1997). However, only a few studies have systematically investigated the dynamic pathology of the stria vascularis during development in animal mutants with cochleosaccular degeneration (Araki et al 2002).…”