Development of Standard Reference Materials to support assessment of iodine status for nutritional and public health purposes

Long, Stephen E.; Catron, Brittany L; Boggs, Ashley S.P.; Tai, Susan S.-C.; Wise, Stephen A.

doi:10.3945/ajcn.115.110361

Cited by 9 publications

(9 citation statements)

References 43 publications

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“…In terms of analytical methodology, the ICP-MS method [ 76 ] is suitable for the analysis of iodine in a variety of foods, as well as dietary supplements, and is known to have good precision and accuracy. Using the ICP-MS method, the USDA contract laboratory has shown that it can generate accurate iodine values that compare well with the iodine values of several NIST-certified reference materials (CRM), notably NIST 1849a Infant/Adult Nutritional Formula and 1548a Typical Diet [ 21 , 78 , 80 ]. For quality control during analysis of samples, the USDA is using these CRM reference materials, as well as in-house control materials cross-validated to the NIST materials.…”

Section: Developing An Iodine Database For Us Foods—recent Progresmentioning

confidence: 99%

“…Also, iodine derived from dietary supplements must be included along with foods in order to accurately assess total intake; therefore, data are needed on the iodine content of supplements [ 20 ]. Robust approaches to developing databases will include choosing appropriate analytical methodology (including use of standard reference materials [ 21 , 22 ]); designing and implementing sampling plans with good coverage of major country-specific contributors (from foods, beverages, dietary supplements, and salt); and publishing the results in database formats or tables that allow linkage with population surveys and individual intake records (such as food frequency questionnaires and 24-h recalls).…”

Section: Introductionmentioning

confidence: 99%

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Development of Databases on Iodine in Foods and Dietary Supplements

et al. 2018

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Iodine is an essential micronutrient required for normal growth and neurodevelopment; thus, an adequate intake of iodine is particularly important for pregnant and lactating women, and throughout childhood. Low levels of iodine in the soil and groundwater are common in many parts of the world, often leading to diets that are low in iodine. Widespread salt iodization has eradicated severe iodine deficiency, but mild-to-moderate deficiency is still prevalent even in many developed countries. To understand patterns of iodine intake and to develop strategies for improving intake, it is important to characterize all sources of dietary iodine, and national databases on the iodine content of major dietary contributors (including foods, beverages, water, salts, and supplements) provide a key information resource. This paper discusses the importance of well-constructed databases on the iodine content of foods, beverages, and dietary supplements; the availability of iodine databases worldwide; and factors related to variability in iodine content that should be considered when developing such databases. We also describe current efforts in iodine database development in the United States, the use of iodine composition data to develop food fortification policies in New Zealand, and how iodine content databases might be used when considering the iodine intake and status of individuals and populations.

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Section: Developing An Iodine Database For Us Foods—recent Progresmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development of Databases on Iodine in Foods and Dietary Supplements

et al. 2018

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“…Either of these human milk CRMs, which would reside in sector 6, could also be analyzed to determine organic nutrients. A reference value for iodine was added recently to SRM 1953 to address this important inorganic nutrient in human milk [98] and to complement the other nutritional elements listed. Yerba mate (SRM 3253), shown in sector 5 of Fig.…”

Section: Future Crm Needs For Organic Nutrientsmentioning

confidence: 99%

Evolution of reference materials for the determination of organic nutrients in food and dietary supplements—a critical review

Wise

Phillips

2018

Anal Bioanal Chem

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For over 40 years, food-matrix certified reference materials (CRMs) have been available for determination of trace element content, and a wide variety of materials are available from most producers of CRMs. However, the availability of food-matrix CRMs for organic nutrients has been more limited. The European Commission (EC) Bureau Communautaire de Référence (BCR) and the National Institute of Standards and Technology (NIST) introduced food-matrix CRMs with values assigned for vitamins and other organic nutrients such as fatty acids and carotenoids in the 1990s. The number of organic nutrients for which values were assigned has increased significantly in the past decade, and the approach and analytical methods used for assignment of the certified values have also evolved. Recently, dietary supplement-matrix CRMs such as multivitamin tablets with values assigned for vitamins and carotenoids, and fish and plant oils with values assigned for fatty acids have appeared. The development, evolution, and improvement of food- and dietary supplement-matrix CRMs for determination of vitamins, carotenoids, and fatty acids are described, with emphasis on CRMs made available in the past 10 years. Recent food and dietary supplement CRMs for the determination of organic nutrients include infant formula, multivitamin tablets, milk and egg powders, breakfast cereal, meat homogenate, blueberries, soy flour, fish and plant oils, dry cat food, and protein drink powder. Many of these food- and supplement-matrix CRMs have values assigned for over 80 organic and inorganic nutrients, toxic elements, proximates, and contaminants. The review provides a critical assessment of the challenges and evolving improvements in the production and the analytical methods used for value assignment of these CRMs. The current status and future needs for additional food- and dietary supplement-matrix CRMs for organic nutrients are also discussed.

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“…Standard Reference Materials (SRMs) are CRMs issued by the NIST. The NIST is developing breast-milk SRMs that are valid over a limited range of iodine concentrations, but breast-milk CRMs or SRMs covering a wider range of iodine concentrations will still be needed (35). The NIST is also developing trimester-specific serum CRMs or SRMs that span the full range of results for all serum tests of thyroid function (35).…”

Section: Development Of Reference Materials For Biological Samplesmentioning

confidence: 99%

Research needs for assessing iodine intake, iodine status, and the effects of maternal iodine supplementation

Ershow

Coates

Swanson

2016

The American Journal of Clinical Nutrition

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The Office of Dietary Supplements of the NIH convened 3 workshops on iodine nutrition in Rockville, Maryland, in 2014. The purpose of the current article is to summarize and briefly discuss a list of research and resource needs developed with the input of workshop participants. This list is composed of the basic, clinical, translational, and population studies required for characterizing the benefits and risks of iodine supplementation, along with related data, analyses, evaluations, methods development, and supporting activities. Ancillary studies designed to use the participant, biological sample, and data resources of ongoing and completed studies (including those not originally concerned with iodine) may provide an efficient, cost-effective means to address some of these research and resource needs. In the United States, the foremost question is whether neurobehavioral development in the offspring of mildly to moderately iodine-deficient women is improved by maternal iodine supplementation during pregnancy. It is important to identify the benefits and risks of iodine supplementation in all population subgroups so that supplementation can be targeted, if necessary, to avoid increasing the risk of thyroid dysfunction and related adverse health effects in those with high iodine intakes. Ultimately, there will be a need for well-designed trials and other studies to assess the impact of maternal supplementation on neurodevelopmental outcomes in the offspring. However, 2 basic information gaps loom ahead of such a study: the development of robust, valid, and convenient biomarkers of individual iodine status and the identification of infant and toddler neurobehavioral development endpoints that are sensitive to mild maternal iodine deficiency during pregnancy and its reversal by supplementation.

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Development of Standard Reference Materials to support assessment of iodine status for nutritional and public health purposes

Cited by 9 publications

References 43 publications

Development of Databases on Iodine in Foods and Dietary Supplements

Development of Databases on Iodine in Foods and Dietary Supplements

Evolution of reference materials for the determination of organic nutrients in food and dietary supplements—a critical review

Research needs for assessing iodine intake, iodine status, and the effects of maternal iodine supplementation

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