Development of sodium alginate/glycerol/tannic acid coated cotton as antimicrobial system

Sharma, Ankita; Verma, Chetna; Mukhopadhyay, Samrat; Gupta, Amlan; Gupta, Bhuvanesh

doi:10.1016/j.ijbiomac.2022.06.168

Cited by 37 publications

(21 citation statements)

References 34 publications

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“…Sharma et al [44] added TA (30 wt%) into SA/Gly and also stated a similar positive effect. And also, Bai et al con rmed that with the increase in TA content, added into PVA/Col hydrogels, cell proliferation is increasing [45]. These differences, between our research and others, may be related to the number of released substances, from both hyaluronic acid and tannic acid.…”

Section: Discussioncontrasting

confidence: 48%

“…The following parameters were set up: 200 mN maximum force, 20 s of the loading time, 15 s of the unloading time, and 5 s of the holding time under maximum force. After each test, temperature drift was allowed for 10 s. The load-displacement curves were determined for each lm (n = 10) and the hardness (H) and reduced Young's modulus (Er) were calculated by the Oliver and Pharr method [45] using integrated software.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

“…RBCs treated with 2% Triton were used as a positive control (i.e., 100% hemolysis) and RBCs incubated without lms as a negative control. According to the literature absorbance values which did not exceed the value of 1 were assumed negative for hemolysis [45].…”

Section: Hemo-and Cytocompatibilitymentioning

confidence: 99%

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Hyaluronic acid/tannic acid films for biomedical application

Wekwejt

Kluczyński

Ronowska

et al. 2022

Preprint

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In this study thin films based on hyaluronic acid (HA) with tannic acid (TA) were investigated in three different weight ratios (80HA/20TA, 50HA/50TA, 20HA/80TA) for potential medical applications. Surface free energy as well as its roughness, mechanical properties, water vapor permeability rate, and antioxidant activity were determined. Moreover, the compatibility with blood and osteoblast cells was investigated. The irritation effect for hyaluronic acid/tannic acid films by in vitro method was also considered. The results showed that the films have low surface free energy (54-42 mJ/m2), and rough surface (Ra 2.92-3.45 nm; Rq 3.84-4.21), and showed antioxidant activity (RSA 26% for 80HA/20TA; 93% for 20HA/80TA). All of the studied compositions of hyaluronic acid/tannic acid films are hemocompatible (hemolysis rate below 2%), however fully cytocompatible are only films based on 50HA/50TA. All films except 80HA/20TA showed appropriate mechanical properties in terms of potential implantation. All samples did not show the irritation effect during the studies using the reconstructed human epidermis.

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Section: Discussioncontrasting

confidence: 48%

Section: Mechanical Propertiesmentioning

confidence: 99%

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Hyaluronic acid/tannic acid films for biomedical application

Wekwejt

Kluczyński

Ronowska

et al. 2022

Preprint

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“…The peak intensity decreases at near 3300 cm −1 and at near 2900 cm −1 which is due to the presence of cotton fibers in the alginate structure. The formation of intermolecular hydrogen bonding between cotton fibers and alginate hydrogel is attained due to the presence of hydroxyl groups and carbonyl groups that may decrease and shifts the intensities of the peaks [ 42 , 43 ].…”

Section: Resultsmentioning

confidence: 99%

“…The characteristic peaks at 2θ = 13° and 21° are associated with alginate [ 50 ] while peaks at 2θ = 15°, 17°, 22° and 34° show the cotton structure which confirms the cotton fiber reinforcement in alginate fibers. The peak intensity at 2θ = 15°, 17°, 22°, and 34° in Figure 7 b decreases as compared to Figure 7 a because 10 wt% cotton fibers were added to alginate fiber as reinforcement which enhances the amorphousness of the hydrogel polymers [ 43 ]. The peaks for cotton reinforced alginate hydrogel fiber are not very sharp which exhibits a semi-crystalline structure.…”

Section: Resultsmentioning

confidence: 99%

Preparation and Characterization of Alginate Hydrogel Fibers Reinforced by Cotton for Biomedical Applications

Azam

Ahmad

et al. 2022

Polymers

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In this study, cotton-reinforced alginate hydrogel fibers were successfully synthesized using the wet spinning technique to improve hydrogel fibers’ mechanical strength and durability. Structural, chemical, and mechanical properties of the prepared fibers were characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray Diffraction, differential scanning calorimeter, and single fiber strength tester. Based on the results obtained from fourier transform infrared spectroscopy and x-ray Diffraction, cotton fibers have been successfully incorporated into the structure of the hydrogel fibers. It was seen from the differential scanning calorimeter results that the incorporation of fibers in the structure even enhanced the thermal stability of the fiber and is viable to be implanted in the human body. Cotton reinforcement in alginate hydrogel fibers increases the modulus up to 56.45 MPa providing significant stiffness and toughness for the hydrogel composite fiber. The tenacity of the fibers increased by increasing the concentration of alginate from 2.1 cN/Tex (1% w/v) to 8.16 cN/Tex (1.5% w/v). Fiber strength increased by 26.75% and water absorbance increased by 120% by incorporating (10% w/w) cotton fibers into the fibrous structure. It was concluded that these cotton-reinforced alginate hydrogel fibers have improved mechanical properties and liquid absorption properties suitable for use in various biomedical applications.

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Surface Immobilization of Oxidized Carboxymethyl Cellulose on Polyurethane for Sustained Drug Delivery

Somani,

Verma,

Nonglang

et al. 2024

Macromolecular Bioscience

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Polyurethane (PU) has a diverse array of customized physical, chemical, mechanical, and structural characteristics, rendering it a superb option for biomedical applications. The current study involves modifying the polyurethane surface by the process of aminolysis (aminolyzed polyurethane; PU‐A), followed by covalently immobilizing Carboxymethyl cellulose (CMC) polymer utilizing Schiff base chemistry. Oxidation of CMC periodically leads to the creation of dialdehyde groups along the CMC chain. When the aldehyde groups on the OCMC contact the amine group on a modified PU surface, they form an imine bond. Scanning electron microscopy (SEM), contact angle, and X‐ray photoelectron spectroscopy (XPS) techniques are employed to analyze and confirm the immobilization of OCMC on aminolyzed PU film (PU‐O). The OCMC gel incorporates Nitrofurantoin (NF) and immobilizes it on the PU surface (PU‐ON), creating an antibacterial PU surface. The confirmation of medication incorporation is achieved using EDX analysis. The varying doses of NF have demonstrated concentration‐dependent bacteriostatic and bactericidal effects on both Gram‐positive and Gram‐negative bacteria, in addition to sustained release. The proposed polyurethane (PU‐ON) surface exhibited excellent infection resistance in in vivo testing. The material exhibited biocompatibility and is well‐suited for biomedical applications.

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Development of sodium alginate/glycerol/tannic acid coated cotton as antimicrobial system

Cited by 37 publications

References 34 publications

Hyaluronic acid/tannic acid films for biomedical application

Hyaluronic acid/tannic acid films for biomedical application

Preparation and Characterization of Alginate Hydrogel Fibers Reinforced by Cotton for Biomedical Applications

Surface Immobilization of Oxidized Carboxymethyl Cellulose on Polyurethane for Sustained Drug Delivery

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