Development of Scrub Nurse Robot for Laparoscopic Surgery

Radical Fixation of Functionalized Carbon Resources: α-sp3C−H Carbamoylation of Tertiary Amines with Aryl Isocyanates

“…Borinamide 24 , whose structure was unambiguously confirmed by X-ray crystallographic analysis, indicates an intermediacy of amidyl radical ii that is captured by Et 3 B (Figure ). − The reason why borinamide 24 was produced in this particular case is unclear, although it is likely that the stability against hydrolysis owing to its structural rigidity enabled the successful isolation . Interestingly, contrary to the previously reported hydroxyalkylation reaction in which only one α-hydrogen was selectively substituted with a carbon atom,3a the present reaction gave not only expected monoanilide but also biscarbamoylated products such as 21 . This may be rationalized by the intramolecular 1,5-hydrogen transfer of amidyl or oxyradical intermediate (Scheme )…”

“…Intensive efforts aimed at the development of new methods for the transformation of α-nitrogen-substituted sp 3 C−H bonds into C−C bonds have led to the emergence of novel approaches to nitrogen-containing molecular frameworks. , In this context, we recently reported the discovery of radical reactions that enabled α-sp 3 C−H hydroxyalkylation of various nitrogen compounds with aldehydes, using Et 3 B/air as the radical source. , …”

Prototype development of scrub nurse robot for laparoscopic surgery

“…Fig. 1A and B shows prototypes of two kinds of SNR and their mechanisms [2], and Table 1 shows the specifications of scrub nurse robot.…”