Development of Schamberg's disease after SARS‐CoV‐2 vaccination

Abstract

Schamberg's disease is one of a group of pigmented purpura diseases. We report a 43‐year‐old woman, who developed Schamberg’s disease after SARS‐CoV‐2 vaccination. Three days after vaccination, a purpuric eruption occurred on the lower extremities, extending to the buttocks, and subsided in 4 weeks. No recurrence was observed thereafter. It is suggested that the vaccination triggered the development of the eruption, which was not merely coincidental. SARS‐CoV‐2 vaccination may stimulate a certain population of T cells, resulting in the development of pigmented purpuric dermatoses.

Cutaneous adverse events following COVID‐19 vaccination: A case series of 30 Japanese patients and a review of 93 Japanese studies

“…A total of 164 non‐injection‐site reactions in 161 patients have been reported in previous case reports and series 7–88 . Patients with systemic lupus erythematosus (SLE) and lupus erythematosus profundus (LEP) showed exacerbation of lupus eruptions after 2 weeks, and other AEs developed several months later.…”