“…For examples, studies have shown that phenyl−tellurocysteine ( I ) was a stronger inhibitor of several human cytochrome P450 isoenzymes compared with phenylselenocysteine and phenylthiocysteine, [11f] 2‐phenyl tellurenyl‐1‐naphthol ( II ) has a significant effect on inhibiting stimulating LTB4 biosynthesis in human neutrophils, [14] water‐soluble 8‐(phenyltellanyl)octyl sulfate sodium ( III ) can efficiently protect against peroxynitrile‐induced oxidation, [15] diaryl telluride ( IV ) at low concentration can present a protective effect on DNA damage without modifying the hemolysis rate, [16] δ‐tocopherol analogue ( V) is an important antioxidant and organotelluride VI is a potent inhibitor of thioredoxin reductase with IC 50 values between 2 and 4 μ M [14,15] (Figure 1). On the other aspect, indole compounds possess impressive antihistaminic, [17] antifungal, [18] antimicrobial, [19] antiallergy, [20] anti‐HIV [21] and anticancer pharmaceutical activities [22] . Owing to the biologically important properties of both organotellurides and indole compounds, it should be highly desirable to synthesize the tellurolated indoles, a class of compounds that have not been extensively investigated.…”