“…Pesticides play an irreplaceable role in controlling the outbreak of diseases, pests, and weeds to improve crop yields and making outstanding contributions to the food security for a growing world population. , Herbicides, which have the advantages of high efficiency, convenience, and speed, are widely used in farmland, gardens, orchards, and uncultivated lands. , Herbicide technicals are often processed into formulations by adding various chemical additives to facilitate the use in harsh environments. , Unfortunately, there have been many problems caused by herbicidal formulations, such as volatilization, leaching, and rain-washing loss, in agricultural application due to the unreasonable formulation design. − Specially, organic solvents, emulsifiers, wetting agents, dispersants, and other additives used in herbicidal formulations usually cause serious phytotoxicity to non-target plants, increased toxicity to mammals, and even polluted surface water and groundwater, resulting in huge risks to ecosystems and human health. − Therefore, it is essential to develop a new herbicidal formulation to reduce off-target losses and harms to human health and environment.…”