Development of Plant-Based Larvicide and Herbal Mosquito Repellent Fast Card with Reference to Identification of the Functional Bioactive Compounds Effective Against Culex Mosquito

Abstract

Warm and humid climate creates ideal conditions for mosquito breeding. The ability of these vectors to spread a number of diseases to humans causes millions of deaths every year. Indiscriminate use of synthetic insecticides leads to the development of resistance in vector mosquitoes and along with this, these pesticides cause biological magni cation of toxic components and affects adversely the non target organisms including human being. Commercially available, chemically manufactured mosquito repellent fast cards are convenient to use and quite effective but burning of such card generates a lot of smoke and might be hazardous to human health in long run. Thus, alternative approaches are to be adopted to control the population load of vector mosquito. The present study reveals the larvicidal effect of Duranta leaf extract against Culex mosquito. In addition to that mosquito repellent fast card has been developed by Duranta-algal mixture that has shown better result than commercially available fast card on the basis of mosquito mortality as well as the amount of gases emitted. Therefore, the active component of Duranta has also been investigated. In Duranta highest area percentage and peak have been shown by propeonic acid in the retention time 18.086 by GC-MS. So, it can be con rmed that the major active ingredient is propionic acid in Duranta which is responsible for the mosquitocidal properties. Occurrence of propionic acid in Duranta has also been con rmed by the HPLC analysis.

RNAi-mediated CHS-2 silencing affects the synthesis of chitin and the formation of the peritrophic membrane in the midgut of Aedes albopictus larvae

“…Several species of mosquitoes have a strong invasive capacity [ 1 ]. At present, mosquito-borne diseases are a great global public health challenge [ 2 , 3 ]. Due to the complexity of mosquito-borne pathogens, eradication of vectors has become one of the more effective strategies for controlling infectious diseases.…”

Novel Sophoridine Derivatives as Potential Larvicidal Agents against Aedes albopictus: Synthesis, Biological Evaluation, Acetylcholinesterase Inhibition, and Morphological Study

“…Tropical and subtropical regions are particularly vulnerable because the warm and humid climate creates ideal conditions for mosquito breeding [1][2][3][4][5]. For example, 120 million individuals have lymphatic filariasis transmitted by Culex spiculosus, and about 80% of them reside in tropical nations including Bangladesh, India, Indonesia, Malaysia, Nigeria, and the Philippines [6]. According to the World Health Organization, the parasitic infection of malaria transmitted by Anopheline mosquitoes causes an estimated 219 million cases worldwide and gives rise to more than 400,000 deaths annually.…”

A Review of Plant-Based Insect Repellents, Their Applications on Textiles and Repellency Test Methods

“…The developed card is found to cause less gas emission than that of commercial one which is better for the human health. Also, it is revealed by the High Performance Liquid Chromatography (HPLC) analysis that propionic acid in Duranta is responsible for the mosquitocidal properties [11].…”