2022
DOI: 10.21037/atm-22-5856
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Development of personalized classifier based on metastasis and the immune microenvironment to predict the prognosis of osteosarcoma patients

Abstract: Background: Osteosarcoma is a common malignant bone tumor with a poor prognosis. The progression and metastasis of osteosarcoma are significantly influenced by the tumor microenvironment (TME). This study aimed to develop a personalized classifier based on metastasis and immune cells in the TME to achieve better prognostic prediction in osteosarcoma.Methods: Firstly, osteosarcoma metastasis-related differentially expressed genes (DEGs) and infiltrating immune cells in the TME were analyzed using a series of bi… Show more

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