Hypertension and diabetes mellitus increase chances of cardiovascular morbidity. Premature atrial contractions (PACs) have been shown to be strong and independent predictors of incident atrial fibrillation and associated complications, like stroke and congestive heart failure. These morbidities are diagnosed only when the patient is already suffering from the symptoms. Consequently, it is of paramount importance to develop new techniques for early diagnosis prior to any deterioration on healthy patients. The cardiovascular system is controlled and influenced, apart from a unique intrinsic system, by the autonomic nervous system. In a study, lagged Poincaré plot analysis revealed significant changes suggestive of decreased parasympathetic modulation in diabetic patients. 1 In this case, increased high frequency and SD1 (which usually denote parasympathetic activity) are found, which can be because of premature atrial contractions.
| C A S E REP ORTThis is a case of a 63-year-old female presenting with diabetes mellitus, hypertension, hypothyroidism, and postmenopausal osteoporosis. She was admitted to the department of Endocrinology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow on 6/10/19 with complains of fever, breathlessness, anxiety, bodyache, with generalized weakness, anorexia, and insomnia, which improved with medication.She was discharged on 9/10/19 and advised medication paracetamol, metformin 500 mg + glimepiride 3 mg tablet (one tablet BD), sitagliptin 50 mg one tablet BD, Inj Insulin Glargine (24 unit at bed time), (levothyroxine (100 µg one tablet OD), amitriptyline (10 mg one tablet HS), citalopram (10 mg one tablet OD), vitamin D3 (60 000 IU twice a week), and telmisartan, pantoprazole + domperidone (one tablet OD).
Investigations and results.Investigations performed were thyroid profile, showing decreased TSH (0.12 Uiu/mL), CBC was normal except increased ESR ( 22 mm/1stThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. percentage of successive intervals that differ by more than 50 milliseconds; RMSSD, square root of the root mean square of the sum of all differences between successive NN intervals; SD1, standard deviation of Poincaré plot perpendicular to the line of identity; SD2, standard deviation of Poincaré plot along the line of identity; SDNN, standard deviation of all NN intervals; SDRR, standard deviation of all RR intervals; SDSD, standard deviation of the differences between successive NN intervals; TSH, thyroid-stimulating hormone; USG, ultrasonography; VLF, very low frequency.
AbstractThis is a case of a 63-year-old female presenting with diabetes mellitus, hypertension, hypothyroidism, and postmenopausal osteoporosis with findings showing abnormal AFT with reduced heart rate variability (HRV) and multiple lobed Poincaré plot, pointing to pre...