Development of MRI Scalar Maps using DWI Images

Abstract

Neuroimaging has been dramatically advanced by diffusion-weighted and diffusion-tensor imaging (DWI/DTI). Moreover, DWI/DTI permits the examination of the brain's microarchitecture. A thorough understanding of the fundamentals is essential to better understanding pathological presences and avoiding misinterpretation of typical DWI/DTI abnormalities. Diffusion-weighted imaging (DWI) is based on the measurement of the thermal Brownian motion of water molecules, and Diffusion tensor imaging (DTI) is an MRI technique that calculates the axonal arrangement of the brain through anisotropic diffusion. FA, AD, RD, and MD maps are used to study the biological signature of white matter in diffusion MRI studies of brain aging, neurodevelopment, and neurologic injuries. These maps are normally expensive on the market because they are generated separately. Using the DIPY library, we will generate FA, AD, RD, and MD maps to make this process more costeffective.