Development of molecularly imprinted biomimetic immunoassay method based on quantum dot marker for detection of phthalates

Wang, Ximo; Chen, Chen; Xu, Longhua; Zhang, Hongyan; Zhou, Xu

doi:10.1080/09540105.2019.1649371

Cited by 11 publications

(6 citation statements)

References 36 publications

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“…The development of SPE technology mainly depends on the innovation of the sorbents. For the extraction and purification of PAEs in edible oils, traditional sorbents for SPE mainly include C18 [ 46 ], primary secondary amine (PSA) [ 43 , 47 , 48 ], and Florisil ® [ 49 , 50 ]. However, conventional SPE sorbents exhibit low adsorption and selectivity.…”

Section: Sample Preparation Methodsmentioning

confidence: 99%

“…By contrast, a molecularly imprinted biomimetic immunoassay can be used for non-immunogenic molecules, which has the advantages of a low cost and easy preparation. Wang et al prepared bionic antibodies and used the molecularly imprinted biomimetic immunoassay method based on a quantum dot maker to detect PAEs in edible oils [ 47 ]. The LOD was 0.011 mg/L, and the sensitivity was 0.136 mg/L.…”

Section: Detection Techniquesmentioning

confidence: 99%

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Current Sample Preparation Methods and Determination Techniques for the Determination of Phthalic Acid Ester Plasticizers in Edible Oils

Zhu

et al. 2023

Molecules

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In the process of production, processing, transportation, and storage of edible oils, the oils inevitably come into contact with plastic products. As a result, plasticizers migrate into edible oils, are harmful to human health, and can exhibit reproductive toxicity. Therefore, the determination of plasticizers in edible oils is very important, and a series of sample preparation methods and determination techniques have been developed for the determination of plasticizers in edible oils. Phthalic acid ester (PAE) plasticizers are the most widely used among all plasticizers. This review aims to provide a comprehensive overview of the sample preparation methods and detection techniques reported for the determination of PAEs in edible oils since 2010, focusing on sample preparation methods of edible oils combined with various separation-based analytical techniques, such as gas chromatography (GC) and liquid chromatography (LC) with different detectors. Furthermore, the advantages, disadvantages, and limitations of these techniques as well as the prospective future developments are also discussed.

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Section: Sample Preparation Methodsmentioning

confidence: 99%

Section: Detection Techniquesmentioning

confidence: 99%

Current Sample Preparation Methods and Determination Techniques for the Determination of Phthalic Acid Ester Plasticizers in Edible Oils

Zhu

et al. 2023

Molecules

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“…A method was reported by Wang et al . for the detection of plasticizer dibutyl phthalate by synthesizing a hydrophilic direct competitive molecularly imprinted polymer and immunoassay method that was developed using water‐soluble carbon dots as a marker [111] . By using the lateral flow immunoassay method, the detection of human heart fatty acid‐binding protein (hFABP) was done by the Savin et al .…”

Section: Applications Of Carbon Dotsmentioning

confidence: 99%

Recent Development in Synthesis of Carbon Dots from Natural Resources and Their Applications in Biomedicine and Multi‐Sensing Platform

et al. 2021

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Carbon has always found a spotlight in human life either in the form of graphite, diamonds, activated charcoal, carbon nanotubes, or carbon dots (CDs). Carbon quantum dots (CQDs) or CDs became the centre of attraction because of their potential applications in biomedical field such as bio‐imaging, drug nanocarriers, gene therapeutics, photosensitizing agents, theranostics and provides other multifunctional diagnostic platforms. There are numerous advantages of CDs due to their biocompatibility, reduced toxicity, water‐solubility, ease of scale‐up, and, most notably their fluorescence properties contrary to other carbon nanostructures. In last few years, significant efforts have been put by various research teams to synthesize and develop nanostructured materials possessing specific functional properties and characteristics. This work focus on the recent developments in the synthetic approaches applied for CDs using environment‐friendly sources. This review also highlights the mechanistic aspects, applications of CDs in biomedicine and a multi‐sensing platform along with challenges and future perspectives of this promising field. The authors believe that this review will help audible researchers to select a suitable environment‐friendly approach for the synthesis of CDs from green sources with required functions and properties. It will also guide researchers to develop a more convenient, efficient, and environment‐friendly method for the synthesis of new tunable carbon dots.

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“…Carbon quantum dots (CDs) have attracted widespread attention because they not only have excellent optical properties and small size characteristics, but also good biocompatibility, low cost and toxicity, so are a good alternative to the traditional heavy metal quantum dots. These properties mean that CDs offer greater prospects for application as fluorescent probes for biological imaging and detection (Cui et al, 2017;Liao et al, 2019;Ren et al, 2019;Wang et al, 2019;Xiao et al, 2015). However, as fluorescence analysis has developed, the shortcomings of single-emission CDs constructed with a single fluorophore have gradually emerged, the detection results being easily affected by environmental changes and instrument interference.…”

Section: Introductionmentioning

confidence: 99%

Detection of dibutyl phthalate in food samples by fluorescence ratio immunosensor based on dual-emission carbon quantum dot labelled aptamers

Wang

Chen

et al. 2020

Food and Agricultural Immunology

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This study reports a fluorescence ratio immunosensor method for detecting dibutyl phthalate (DBP) sensitively and specifically using dual-emission carbon quantum dots labelled with amino-modified nucleic acid aptamers. Under optimal experimental conditions, the linearity range of the method for detecting DBP was from 12.5 to 1500 μg/L, with a limit of detection of 5.0 μg/L. Compared with detection results for two structural analogues, this method showed good specificity for DBP. Liquor samples spiked with DBP measured by this method exhibited a standard recovery of 93.2% to 112.4% with a relative standard deviation of 1.59% to 4.54%. The method was used to determine the DBP content in edible oil samples, providing results not significantly different from those obtained by gas chromatography. Compared with the single wavelength emission method, this method had a stronger antiinterference ability and provided more accurate results, so can be used for highly sensitive detection of DBP in food samples.

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Development of molecularly imprinted biomimetic immunoassay method based on quantum dot marker for detection of phthalates

Abstract: Development of molecularly imprinted biomimetic immunoassay method based on quantum dot marker for detection of phthalates,

Cited by 11 publications

References 36 publications

Current Sample Preparation Methods and Determination Techniques for the Determination of Phthalic Acid Ester Plasticizers in Edible Oils

Current Sample Preparation Methods and Determination Techniques for the Determination of Phthalic Acid Ester Plasticizers in Edible Oils

Recent Development in Synthesis of Carbon Dots from Natural Resources and Their Applications in Biomedicine and Multi‐Sensing Platform

Detection of dibutyl phthalate in food samples by fluorescence ratio immunosensor based on dual-emission carbon quantum dot labelled aptamers

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