Abstract:Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in feedlot cattle. Bovine herpesvirus-1 (BHV-1) is one of the main culprits of BRD; however, research on BHV-1 is hampered by the lack of suitable models for infection and drug testing. In this study, we established a novel bovine tracheal organoid culture grown in a basement membrane extract type 2 (BME2) matrix and compared it with the air–liquid interface (ALI) culture system. After differentiation, the matrix-embedded organoid… Show more
“…The selected articles in this Special Issue also include new themes, such as animal tissue organoids, to introduce organoid technology into the veterinary infectious disease field and livestock industry. Quah and colleagues [12] established organoids from bovine trachea and characterised the models using single-cell RNA sequencing. The authors assessed the effect of immune modulation on the susceptibility of epithelial cells to viral infection.…”
“Organoids Are Us” is an annual one-day symposium organised to highlight the advances in science and medicine that are the direct result of organoid technology [...]
“…The selected articles in this Special Issue also include new themes, such as animal tissue organoids, to introduce organoid technology into the veterinary infectious disease field and livestock industry. Quah and colleagues [12] established organoids from bovine trachea and characterised the models using single-cell RNA sequencing. The authors assessed the effect of immune modulation on the susceptibility of epithelial cells to viral infection.…”
“Organoids Are Us” is an annual one-day symposium organised to highlight the advances in science and medicine that are the direct result of organoid technology [...]
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