Development of matrix certified reference material for accurate determination of docosahexaenoic acid in milk powder

Jian, Zhou; Yang, Mujie; Li, Fukai; Wang, Min; Zhang, Yaoguang; Wei, Min; Li, Xingjia; Qi, Xiaoru; Bai, Xiao-Bo; chai, Yanbin

doi:10.1016/j.foodchem.2022.135012

Cited by 6 publications

(6 citation statements)

References 15 publications

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“… where s 1 represents the between-bottle variance, s 2 represents the within-bottle variance, and n is 3. Additionally, the target measurement uncertainty of the CRM ( u trg ) was expected to be around 3.0 μg/kg . The samples showed a negligible contribution to the uncertainty of the certified value because the s r was smaller than , Therefore, the results confirmed that the CRMs were homogeneous for AFB 1 at the 95% confidence level, with the minimum sampling amount for the CRM of 1.0 g.…”

Section: Resultsmentioning

confidence: 65%

“…As mentioned above, in the case of homogeneity, both s bb and s r were utilized to evaluate the homogeneity of the CRM samples. Because the value of s r was larger than that of s bb , the s r was adopted as the component of uncertainty ( u bb ). , It could be found that these AFB 1 CRM samples were homogeneous with an uncertainty level of 0.40 μg/kg (Table ). Moreover, the uncertainty of stability included the uncertainty of short-term stability ( u sts ) and the uncertainty of long-term stability ( u lts ).…”

Section: Resultsmentioning

confidence: 99%

“…Additionally, the target measurement uncertainty of the CRM (u trg ) was expected to be around 3.0 μg/kg. 20 The samples showed a negligible contribution to the uncertainty of the certified value because the s r was smaller than…”

Section: Homogeneity Assessmentmentioning

confidence: 99%

“…It has been recommended to food testing laboratories by the accreditation body that traceable certified reference materials (CRMs) could be used in the quality control . Well-characterized CRMs are often essential to evaluate the performance of existing methods and to develop new analytical methods. − Moreover, CRMs are the basic pillars to achieve metrological traceability in the frameworks of international agreed standards . Hence, matrix CRMs, which serve as key tools for achieving these objectives, are highly demanded and rapidly expanded. , Therefore, the development of matrix CRMs for AFB 1 analysis is of great interest to both customers and suppliers of CRMs.…”

Section: Introductionmentioning

confidence: 99%

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Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B₁ in Peanut Oils

Zhao,

Li,

et al. 2024

ACS Food Sci. Technol.

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Aflatoxin B 1 in a peanut oil matrix certified reference material (CRM, GBW10176) has been issued for accurate determination of aflatoxin B 1 in real samples. This matrix CRM was prepared from commercial peanut oils naturally contaminated by aflatoxin B 1 , with the aid of a liquid−liquid extraction process. Specially, the certified value of CRM was determined using two individual approaches, liquid chromatography−isotope dilution tandem mass spectrometry and standard addition liquid chromatography−fluorescence detection techniques. More importantly, assessments of homogeneity and short-and long-term stabilities confirmed that the GBW10176 CRM was sufficiently homogeneous between packages or within package, and it could be stable up to 7 days stored below 50 °C or 18 months at 4 °C. The metrological traceability of GBW10176 was ensured by the application of pure aflatoxin B 1 (GBW10172). Its uncertainty was evaluated with the contributions from the characterization, homogeneity, and stability. Resultantly, the certified value of the aflatoxin B 1 CRM (GBW10176) was 23.4 μg/kg with an uncertainty of 3.1 μg/kg (k = 2).

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Section: Resultsmentioning

confidence: 65%

Section: Resultsmentioning

confidence: 99%

Section: Homogeneity Assessmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B₁ in Peanut Oils

Zhao,

Li,

et al. 2024

ACS Food Sci. Technol.

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“…The measurement results were linearly fitted to show the stability trend, and regression analysis statistical tests were performed on the data. According to ISO guideline 35:2007 [38], the t test was used to calculate the significance of the slope a, where s(a) is the uncertainty of the slope a, as calculated using Equations ( 5) and (6).…”

Section: Parameters Valuesmentioning

confidence: 99%

Development of a Purity Certified Reference Material for Vinyl Acetate

He,

Gao,

et al. 2023

Molecules

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Vinyl acetate is a restricted substance in food products. The quantification of the organic impurities in vinyl acetate is a major problem due to its activity, instability, and volatility. In this paper, while using the mass balance method to determine the purity of vinyl acetate, an improved method was established for the determination of the content of three impurities in vinyl acetate reference material, and the GC-FID peak area normalization for vinyl acetate was calibrated. The three trace organic impurities were identified by gas chromatography tandem high-resolution mass spectrometry to be methyl acetate, ethyl acetate, and vinyl propionate. The content and relative correction factors for the three organic impurities were measured. The purity of vinyl acetate determined by the mass balance method was 99.90% with an expanded uncertainty of 0.30%, and the total content of organic impurities was 0.08% with a relative correction factor of 1.23%. The vinyl acetate reference material has been approved as a national certified reference material in China as GBW (E) 062710.

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Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

Huang,

Liu,

Zhou

et al. 2024

Accred Qual Assur

Self Cite

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In this study, two different concentrations of matrix certified reference materials (CRMs) were produced for the accurate measurement of aflatoxin M1(AFM1) in milk powder((GBW(E) 100552, GBW(E) 100553)). The raw material was obtained by feeding cows with positive drugs. The homogeneity, stability and characterization of this matrix CRMs were examined by liquid chromatography tandem mass spectrometry with isotope-labeled internal standard method. The certified value for the low concentration of AFM1 in milk powder was 2.45 µg/kg with an uncertainty of 0.43 µg/kg (coverage factor k=2, at 95% confidence). The certified value for the high concentration of AFM1 in milk powder was 3.45 µg/kg with an expanded uncertainty of 0.49 µg/kg (coverage factor k=2, at 95% confidence). In addition, the samples were evaluated in detail for homogeneity, long-term stability at -80°C for 6 months, and short-term stability at 4°C for 7 days. The results showed that the samples were stable under the above conditions.

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Development of matrix certified reference material for accurate determination of docosahexaenoic acid in milk powder

Cited by 6 publications

References 15 publications

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B₁ in Peanut Oils

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B₁ in Peanut Oils

Development of a Purity Certified Reference Material for Vinyl Acetate

Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

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Development of matrix certified reference material for accurate determination of docosahexaenoic acid in milk powder

Cited by 6 publications

References 15 publications

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B1 in Peanut Oils

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B1 in Peanut Oils

Development of a Purity Certified Reference Material for Vinyl Acetate

Certification of a novel matrix reference material for accurate measurements of aflatoxin M1 in milk powder

Contact Info

Product

Resources

About

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B₁ in Peanut Oils

Development of a Matrix Certified Reference Material for Quantification of Aflatoxin B₁ in Peanut Oils