Development of malignant lymphoma after metal-on-metal hip replacement: a case report and review of the literature

McCarthy, Catherine; Uchihara, Yoshinobu; Vlychou, Marianna; Grammatopoulos, George; Athanasou, Nick

doi:10.1007/s00256-017-2612-y

Cited by 13 publications

(5 citation statements)

References 41 publications

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“…Each type of a base material offers different advantages and disadvantages. Metals, for example, exhibit excellent mechanical properties and are thus frequently used as bone or joint replacements [12]. Due to their large expansion coefficient, however, it is necessary to replace them with ceramics or some other material in applications where the increase of volume with rising temperature would prove problematic [13].…”

Section: Introductionmentioning

confidence: 99%

Surface Modification of Polymer Substrates for Biomedical Applications

2017

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While polymers are widely utilized materials in the biomedical industry, they are rarely used in an unmodified state. Some kind of a surface treatment is often necessary to achieve properties suitable for specific applications. There are multiple methods of surface treatment, each with their own pros and cons, such as plasma and laser treatment, UV lamp modification, etching, grafting, metallization, ion sputtering and others. An appropriate treatment can change the physico-chemical properties of the surface of a polymer in a way that makes it attractive for a variety of biological compounds, or, on the contrary, makes the polymer exhibit antibacterial or cytotoxic properties, thus making the polymer usable in a variety of biomedical applications. This review examines four popular methods of polymer surface modification: laser treatment, ion implantation, plasma treatment and nanoparticle grafting. Surface treatment-induced changes of the physico-chemical properties, morphology, chemical composition and biocompatibility of a variety of polymer substrates are studied. Relevant biological methods are used to determine the influence of various surface treatments and grafting processes on the biocompatibility of the new surfaces—mammalian cell adhesion and proliferation is studied as well as other potential applications of the surface-treated polymer substrates in the biomedical industry.

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Section: Introductionmentioning

confidence: 99%

Surface Modification of Polymer Substrates for Biomedical Applications

2017

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“…For patients undergoing hip replacement operation, getting out of bed as soon as possible after surgery can effectively prevent deep vein thrombosis of the lower extremities [ 17 ]. Lower extremity deep venous thrombosis is the main complication of hip arthroplasty, but postoperative pain leads most patients to dread early functional exercise, which leads to a series of complications [ 18 ]. Pain affects the mood, confidence and expectation of future healthy life of patients undergoing hip arthroplasty.…”

Section: Discussionmentioning

confidence: 99%

Effect of Painless Rehabilitation Nursing for Hip Replacement Patients

Zhao

Bai

Yang

2022

Computational and Mathematical Methods in Medicine

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Objective. To analyze the effect of painless rehabilitation nursing for hip replacement patients. Method. 124 elderly patients who underwent total knee arthroplasty in our hospital from June 2019 to June 2020 were selected as study subjects. They were randomly divided into observation group and control group. The control group was given routine nursing care, and the observation group was given painless rehabilitation care on the basis of the control group. Knee circumference, knee pain, knee function, agitation and sleep duration were recorded and compared between the two groups. Results. The changes of knee circumference diametral in both groups were significantly decreased at 1, 3 and 7 days after operation; The changes of knee circumference diametral in the observation group were significantly smaller than those in the control group at 3,7 days after operation (P <0.05). VAS (Visual Analogue Scale) scores at 1, 3 and 7 d after operation were significantly decreased in both groups; The score of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P <0.05). HSS (Hospital for special surgery) scores increased significantly in both groups at 1 week, 1 month, 3 months and 6 months after operation. All the comparisons were statistically significant (P <0.05); HSS scores of observation group were significantly higher than control group at 1 week, 1 month, 3 months and 6 months after surgery. The difference was statistically significant (P <0.05). The agitation rate of the observation group was lower than that of the control group (P <0.05). Compared with the control group, the sleep time of observation group increased significantly in each period, with statistically significant difference (P <0.05). Conclusion. Perioperative painless rehabilitation nursing interventions for patients with hip replacement could significantly relieve swelling and pain, it was helpful for the patients to recover the function of knee joint after operation and worthy of clinical application.

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“…adjacent to a prosthetic implant [20,21]. Epidemiologic studies about malignant tumors at a distance from the implants show an increased risk of lymphoma and leukemias related to old MoM implants [20,21].…”

Section: Discussionmentioning

confidence: 99%

N-Acetyl-Cysteine Reduces Blood Chromium and Cobalt Levels in Metal-on-Metal Hip Arthroplasty

D’Ambrosi

Ursino

2020

Arthroplasty Today

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The most common reasons for revision of metal-on-metal hip arthroplasty are aseptic loosening and metal reaction. Failure of a metal-on-metal implant due to the aggressive destruction of periprosthetic tissues may require extensive reconstruction procedures. The aim of this case report is to describe the treatment in an asymptomatic patient with high levels of chromium and cobalt, using chelation therapy. The rational use of N-acetyl-cysteine (NAC) involves thiol groups to chelate sites for metals. More than 10 years after the metal-on-metal hip arthroplasty, the patient did not have to undergo revision surgery; the levels of the ions in the blood were considerably lowered (chromium from 4.

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Development of malignant lymphoma after metal-on-metal hip replacement: a case report and review of the literature

Cited by 13 publications

References 41 publications

Surface Modification of Polymer Substrates for Biomedical Applications

Surface Modification of Polymer Substrates for Biomedical Applications

Effect of Painless Rehabilitation Nursing for Hip Replacement Patients

N-Acetyl-Cysteine Reduces Blood Chromium and Cobalt Levels in Metal-on-Metal Hip Arthroplasty

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