“…• One dimensional nanoparticles: One dimensional system (thin films) has been used for decades. Thin films (sizes 1-100 nm) or monolayer is common in the field of solar cells offering, different technological applications, such as chemical and biological sensors, information storage systems, magneto-optic and optical device, fiber optic systems [30]. Functionalization enhanced solubility, penetration to cell cytoplasm, and to nucleus, as carrier for gene delivery, peptide delivery [30], [46] Dendrimer <10 Long circulatory, controlled delivery of bioactives, targeted delivery of bioactives to microphages [30], [46] Liposome 50-100 Long circulatory, offer passive and active delivery of gene, protein, peptide, and various others [46] Metallic nanoparticles…”