This review determines various optimization techniques which are used commercially for pharmaceutical formulations. A
glance on the terminology used in optimization, about the software which is used for design of experiments and
information regarding optimization parameters.In this various experimental designs are listed such as Factorial design, fractional factorial
design,mixture design, star design, Plackett-Burmann design,Central composite design, Box-Behnken design, Taguchi design, D-Optimal
design,sequential optimization design etc.In this it describes about the future scope of the optimization techniques and also various types of
experimental designs used for various research works were listed. Thus optimization techniques plays key role in the formulation of various
pharmaceutical formulations which brings prots and save time for pharmaceutical industry.