Development of l-lactate dehydrogenase biosensor based on porous silicon resonant microcavities as fluorescence enhancers

Jenie, S. N. Aisyiyah; Prieto‐Simón, Beatriz; Voelcker, Nicolas H.

doi:10.1016/j.bios.2015.07.025

Cited by 40 publications

(30 citation statements)

References 55 publications

(75 reference statements)

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“…Last but not least, we provide a screenshot of the rising demand of pSi structures toward the development of implantable medical diagnostic devices . Different pSi‐based biosensors, such as immunosensors, aptasensors, and DNA hybridization and enzyme biosensors, have been engineered for the enhanced detection of those specific bioanalytes that are relevant to multiple malignancies like cancer, chronic wounds, or cardiovascular diseases.…”

Section: Introductionmentioning

confidence: 99%

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Tieu

Alba

Elnathan

et al. 2018

Advanced Therapeutics

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101

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This review provides a perspective on porous silicon (pSi)-based nanomaterials including nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy, imaging, and sensing, with a focus on their effective use in future clinical settings. The achievement of both controlled geometry and architecture, and surface chemistry motifs, are presented as the two key parameters that dictate the nature of interactions with the biological entities. The authors discuss the role of the degradation kinetics in a biological environment into nontoxic by-products. pSi is presented as increasingly fulfilling a central task in various biomedical applications and clinical settings, owing to its unique physiochemical properties.

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Section: Introductionmentioning

confidence: 99%

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Tieu

Alba

Elnathan

et al. 2018

Advanced Therapeutics

Self Cite

101

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show abstract

“…Porous silicon (PS), since its discovery [1–4], has had huge development for various applications, like gas sensors [5], solar cells [6, 7], Bragg reflectors [8], biosensors [9–12], photocatalysis [13], tissue engineering [14], and cell growth [15–18], among others. Particularly, the last two applications have attracted researcher interest in studying the properties of PS as a host matrix Hydroxyapatite (HA) and its implementation in the development of processes leading to bone regeneration.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of porous silicon as hydroxyapatite host matrix of biomedical applications

et al. 2017

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In this work, porous-silicon samples were prepared by electrochemical etching on p-type (B-doped) Silicon (Si) wafers. Hydrofluoric acid (HF)-ethanol (C2H5OH) [HF:Et] and Hydrofluoric acid (HF)-dimethylformamide (DMF-C3H7NO) [HF:DMF] solution concentrations were varied between [1:2]—[1:3] and [1:7]—[1:9], respectively. Effects of synthesis parameters, like current density, solution concentrations, reaction time, on morphological properties were studied by scanning electron microscopy (SEM) and atomic force microscopy (AFM) measurements. Pore sizes varying from 20 nm to micrometers were obtained for long reaction times and [HF:Et] [1:2] concentrations; while pore sizes in the same order were observed for [HF:DMF] [1:7], but for shorter reaction time. Greater surface uniformity and pore distribution was obtained for a current density of around 8 mA/cm2 using solutions with DMF. A correlation between reflectance measurements and pore size is presented. The porous-silicon samples were used as substrate for hydroxyapatite growth by sol-gel method. X-ray diffraction (XRD) and SEM were used to characterize the layers grown. It was found that the layer topography obtained on PS samples was characterized by the evidence of Hydroxyapatite in the inter-pore regions and over the surface.

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“…S4B †), illustrating the possibility to detect trace amounts of rLDH at the present condition. Such a LOD was more sensitive than the reported ones by using molecular beacon DNA molecule, 21 porous silicon microcavities, 22 pyruvate and NADH as substrate, 23 CdTe/CdS QDs 24 and so on (Table S1 †). Yang et al had explored a highly selective uorescent probe for LDH based on CdTe quantum dots, where the linear calibration plots of the activity of LDH were obtained from 250 to 6000 U L À1 .…”

Section: Resultsmentioning

confidence: 82%

A highly selective and sensitive fluorescent probe for lactate dehydrogenase based on ultrabright adenosine monophosphate capped gold nanoclusters

Liu

2017

RSC Adv.

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Development of l-lactate dehydrogenase biosensor based on porous silicon resonant microcavities as fluorescence enhancers

Cited by 40 publications

References 55 publications

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Synthesis and characterization of porous silicon as hydroxyapatite host matrix of biomedical applications

A highly selective and sensitive fluorescent probe for lactate dehydrogenase based on ultrabright adenosine monophosphate capped gold nanoclusters

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