Development of hydrophilic NbCuSi(N) &amp;TiAlNb(N) coatings as a new strategy for medical implants modification

Kravchenko, Yaroslav; Garkusha, I.E.; Taran, A. V.; Coy, Emerson; Iatsunskyi, Igor; Diedkova, Kateryna; Roshchupkin, Anton; Tymoshenko, Oleksandr; Pogorielov, Мaksym; Misiruk, Ivan

doi:10.1016/j.ceramint.2022.09.290

Cited by 10 publications

(4 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As it was mentioned above, the case when the interaction between silver atoms and Ti2C sample is described through the Lennard-Jones pair potential, simulating deposition onto hydrophobic surface was also considered. We assume that for the formation of individual silver nanoparticles on the surface of a twodimensional material it is necessary to simulate the conditions under which the contact angle of the surface silver atoms would be close to 180 (a situation corresponding to a hydrophobic surface) [18][19][20]. Since experiments with a metallic bond in the system led to a contact angle close to 0 (Ag atoms completely "spread" over the surface of Ti2C), it can be expected that the required conditions of hydrophobicity will be observed when the forces of interaction between silver atoms will significantly exceed the Ag-MXene interaction.…”

Section: Deposition Onto Surface With Hydrophobic Propertiesmentioning

confidence: 99%

Atomistic Simulation of Ti2C MXene Decoration with Ag Nanoparticles

Kravchenko¹,

Taran²,

Shvets³

et al. 2023

J. Nano- Electron. Phys.

View full text Add to dashboard Cite

We report the numerical scheme that was developed within the framework of classical molecular dynamics methods for atomistic simulation of the deposition of Ag atoms onto the surface of two-dimensional (2D) titanium carbide Ti2C (MXene) and the growth of silver nanoparticles (NP). Developed model adopts hybrid interatomic potential, where interactions between metal atoms and between metal-carbon are described within different methods. Proposed model can be used to study similar systems consisting of other metals, as well as two-dimensional carbides Ti(n + 1)Cn with n  2 and 3. Experiments on simulation of the deposition of silver atoms onto the surface of two-dimensional titanium carbide Ti2C with three different values of the growth surface area were performed. To investigate the peculiarities of nanoparticle formation and growth processes, two types of interaction between Ti2C and Ag atoms with the metallic-type bonding and Van der Waals forces were considered. Considered cases simulate deposition onto hydrophilic and hydrophobic surfaces, respectively. It is shown that in case of hydrophilic-type of interaction Ag thin film growth on the substrate, while in case of hydrophobic surface, separate nanoparticles are formed. A modeled sample of the system with a silver nanoparticle formed on the surface of two-dimensional titanium carbide was obtained, and forces of interaction between the Ti2C surface and NPs were calculated. In addition to the stationary case, the MXene-NP interaction was also considered under external loading. The friction forces between the nanoparticle and Ti2C were calculated at three different magnitudes of the external load. It is shown that translational movement of the nanoparticle on the MXene surface observed in the case with largest magnitude of external load.

show abstract

Section: Deposition Onto Surface With Hydrophobic Propertiesmentioning

confidence: 99%

Atomistic Simulation of Ti2C MXene Decoration with Ag Nanoparticles

Kravchenko¹,

Taran²,

Shvets³

et al. 2023

J. Nano- Electron. Phys.

View full text Add to dashboard Cite

show abstract

“…Coating technology is often applied to enhance the properties of the materials that are involved in mechanical contacts, to modify their tribological properties, and to improve wear resistance, adhesion, friction, etc [1]. Furthermore, coatings are also used to achieve the desired level of biocompatibility of implants [2,3], to obtain needed optical properties [4], to enable triboelectric energy harvesting [5], and for many other technologies. Therefore, development of experimental, numerical and analytical techniques for the modelling and studying of materials with a layered structure is an important topic in various fields of science and technology.…”

Section: Introductionmentioning

confidence: 99%

Experimental Verification of the Boundary Element Method for Adhesive Contacts of a Coated Elastic Half-Space

2023

View full text Add to dashboard Cite

We consider analytical, numerical, and experimental approaches developed to describe the mechanical contact between a rigid indenter and an elastic half-space coated with an elastic layer. Numerical simulations of the indentation process were performed using the recently generalized boundary element method (BEM). Analytical approximation of the dependence of contact stiffness on the indenter diameter was used to verify the results of BEM simulations. Adhesive contacts of hard indenters of different shapes with soft rubber layers have been experimentally studied using specially designed laboratory equipment. The comparison of the results from all three implemented methods shows good agreement of the obtained data, thus supporting the generalized BEM simulation technique developed for the JKR limit of very small range of action of adhesive forces. It was shown that the half-space approximation is asymptotical at high ratios of layer thickness h to cylindrical indenter diameter D; however, it is very slowly. Thus, at the ratio h/D = 3.22, the half-space approximation leads to 20% lower contact stiffness compared with that obtained for finite thickness using both an experiment and simulation.

show abstract

“…The uncoated nitinol surface demonstrated high biocompatibility and adequate adhesion of the fibroblast on day 1 after seeding with sufficient proliferation during the seven days of the experiment ( Figure 9 —CCK-8 assay diagram). We noticed a minor difference between the nitinol and positive control groups that could reflect the hydrophobic nature of the metal surface [ 42 ]. The PEO-1 and PEO-2 treatment regimens demonstrated better cell adhesion and increased fibroblast proliferation.…”

Section: Resultsmentioning

confidence: 99%

Nanodiamond Decorated PEO Oxide Coatings on NiTi Alloy

Grundsteins,

Diedkova,

Korniienko

et al. 2023

Nanomaterials

Self Cite

View full text Add to dashboard Cite

Cardiovascular diseases (CVDs) remain a leading cause of death in the European population, primarily attributed to atherosclerosis and subsequent complications. Although statin drugs effectively prevent atherosclerosis, they fail to reduce plaque size and vascular stenosis. Bare metal stents (BMS) have shown promise in acute coronary disease treatment but are associated with restenosis in the stent. Drug-eluting stents (DES) have improved restenosis rates but present long-term complications. To overcome these limitations, nanomaterial-based modifications of the stent surfaces have been explored. This study focuses on the incorporation of detonation nanodiamonds (NDs) into a plasma electrolytic oxidation (PEO) coating on nitinol stents to enhance their performance. The functionalized ND showed a high surface-to-volume ratio and was incorporated into the oxide layer to mimic high-density lipoproteins (HDL) for reverse cholesterol transport (RCT). We provide substantial characterization of DND, including stability in two media (acetone and water), Fourier transmission infrared spectroscopy, and nanoparticle tracking analysis. The characterization of the modified ND revealed successful functionalization and adequate suspension stability. Scanning electron microscopy with EDX demonstrated successful incorporation of DND into the ceramic layer, but the formation of a porous surface is possible only in the high-voltage PEO. The biological assessment demonstrated the biocompatibility of the decorated nitinol surface with enhanced cell adhesion and proliferation. This study presents a novel approach to improving the performance of nitinol stents using ND-based surface modifications, providing a promising avenue for cardiovascular disease.

show abstract

Development of hydrophilic NbCuSi(N) &TiAlNb(N) coatings as a new strategy for medical implants modification

Cited by 10 publications

References 43 publications

Atomistic Simulation of Ti2C MXene Decoration with Ag Nanoparticles

Atomistic Simulation of Ti2C MXene Decoration with Ag Nanoparticles

Experimental Verification of the Boundary Element Method for Adhesive Contacts of a Coated Elastic Half-Space

Nanodiamond Decorated PEO Oxide Coatings on NiTi Alloy

Contact Info

Product

Resources

About