Development of human endogenous retrovirus type K‐ related treatments for human diseases
Lu Dai,
Jiaojiao Fan,
Zhiqiang Qin
Abstract:Human endogenous retroviruses (HERVs) constitute approximately 8% of the human genome and have long been regarded as silent passengers within our genomes. However, the reactivation of HERVs has been increasingly linked to a range of human diseases, particularly the HERV‐K (HML‐2) family. Many studies are dedicated to elucidating the potential role of HERV‐K in pathogenicity. While the underlying mechanisms require further investigation, targeting HERV‐K transactivation emerges as a promising avenue for treatin… Show more
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