Development of honey hydrogel dressing for enhanced wound healing

Yusof, Norimah; Hafiza, A.H. Ainul; Zohdi, Rozaini Mohd; Bakar, Zuki Abu

doi:10.1016/j.radphyschem.2007.02.107

Cited by 65 publications

(37 citation statements)

References 8 publications

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“…Table 3 shows commercial antibacterial wound dressing materials containing these bioactive materials 61. Recent developments in wound dressing materials and their production methods as well as the ingredients used have been reviewed 62–75…”

Section: Wound Dressings and Their Propertiesmentioning

confidence: 99%

A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages

Zahedi

Rezaeian

Siadat

et al. 2009

Polymers for Advanced Techs

750

633

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Wound dressings have experienced continuous and significant changes since the ancient times. The development starts with the use of natural materials to simply cover the wounds to the materials of the present time that could be specially made to exhibit various extraordinary functions. The modern bandage materials made of electrospun biopolymers contain various active compounds that are beneficial to the healing of wounds. These materials are fibrous in nature, with the size of fibers segments ranging from tens of nanometers to micrometers. With the right choices of biopolymers used for these fibrous materials, they could enhance the healing of wounds significantly compared with the conventional fibrous dressing materials, such as gauze. These bandages could be made such that they contain bioactive ingredients, such as antimicrobial, antibacterial, and antiinflammatory agents, which could be released to the wounds enhancing their healing. In an active wound dressing (AWD), the main purpose is to control the biochemical states of a wound in order to aid its healing process. This review provides an overview of different types of wounds, effective parameters in wound healing and different types of wound dressing materials with a special emphasis paid to those prepared by electrospinning.

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Section: Wound Dressings and Their Propertiesmentioning

confidence: 99%

A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages

Zahedi

Rezaeian

Siadat

et al. 2009

Polymers for Advanced Techs

750

633

View full text Add to dashboard Cite

show abstract

“…Polyvinyl pyrrolidone-based hydrogels were also developed and employed for the successful application of honey in wound treatment, which exhibited greater healing compared with silver sulphadiazine cream [40]. This hydrogel is also utilized in the application of iodine [41]. Hydrogels of alginate, cellulose, and poloxamer were also used in the treatment of wounds [42][43][44].…”

Section: Hydrogels For Transdermal Delivery Of Drugsmentioning

confidence: 99%

Hydrogels and Their Combination with Liposomes, Niosomes, or Transfersomes for Dermal and Transdermal Drug Delivery

Ibrahim¹,

Nair²,

Al‐Dhubiab³

et al. 2017

Liposomes

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Polymeric networks that retain and absorb substantial amount of water or biological fluids and resemble as a biological tissue are defined as hydrogels. On the other hand, liposomes, transfersomes and niosomes are lipid carriers, which represent one of the major research and development focus areas of the pharmaceutical industry. They have great potential as lipid vehicles that are able to enhance permeation of drugs across the intact skin and can act as local depot for the drug to sustain and control its delivery. Lipid carrier and hydrogel combinations offer transdermal drug delivery of great potential to enhance systemic effects of both hydrophilic and lipophilic drugs. Also, lipid carriers can target drugs to skin appendages and improve transdermal delivery. Lipid carrier proform systems in the form of gelly liquid crystals can also be used transdermally for better drug absorption enhancement. This review highlights the potential of hydrogels and emulgels with or without lipid nanocarriers for dermal and transdermal application.

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“…Strains of the latter bacterium were not detectable after 24h in contact with honey, which may be applied topically to wounds. The antimicrobial properties of honey irradiated at 25 and 50 kGy and stored in a cool dark place, could be maintained for up to two years [138]. When S. interitidis was incubated with honey at dilutions up to 1:8, bacterial adherence to intestinal epithelial cells was prevented in vitro, but attachment occurred when epithelial cells were incubated with honey [139].…”

Section: Honeymentioning

confidence: 99%

Ancient Procedures for the High-Tech World: Health Benefits and Antimicrobial Compounds from the Mediterranean Empires

Carvalho¹,

Caramujo²

2008

TOBIOTJ

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This paper reviews the benefits of the Mediterranean diet and methods developed for food processing and preservation during the time of the ancient empires. In Antiquity, trees and herbs were harvested for culinary and medicinal purposes, and from the everyday handling of products and keen observation, a great body of wisdom was derived by philosophers and physicians. With modern day techniques, the suspected properties of compounds have been investigated and the beneficial properties tested. From these studies it is apparent that olive oil, herbs, essential oils and metals, when used with the backing of scientific knowledge can improve human health and the standards of living while respecting the environment. Nowadays, proliferation of disinfectants and antimicrobial agents in domestic, industrial and medical environments has contributed to the appearance of resistant microbial strains and of new pathogens. Since regulators have restricted the use and concentrations of many preservatives, sanitizers, and antimicrobial agents, the food industry is facing a problem to extend the shelf-life of products, and to keep the manufacturing environment clean. The application of natural compounds and simple techniques developed by ancient Mediterranean civilizations may prove as useful as more modern synthetic substances, thus avoiding potential threats to human health and the environment.

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Development of honey hydrogel dressing for enhanced wound healing

Cited by 65 publications

References 8 publications

A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages

A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages

Hydrogels and Their Combination with Liposomes, Niosomes, or Transfersomes for Dermal and Transdermal Drug Delivery

Ancient Procedures for the High-Tech World: Health Benefits and Antimicrobial Compounds from the Mediterranean Empires

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