Development of engineered Candida tropicalis strain for efficient corncob-based xylitol-ethanol biorefinery
Anup Kumar Singh,
Farha Deeba,
Mohit Kumar
et al.
Abstract:Background
Xylitol has a wide range of applications in the pharmaceuticals, cosmetic, food and beverage industry. Microbial xylitol production reduces the risk of contamination and is considered as environment friendly and sustainable compared to the chemical method. In this study, random mutagenesis and genetic engineering approaches were employed to develop Candida tropicalis strains with reduced xylitol dehydrogenase (XDH) activity to eliminate co-substrate requirement for corn cob-based xyl… Show more
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