Development of Electrochemical Platform Based on Carbon Nanotubes Decorated with Zirconium Oxide Nanoparticles for Determination of Nebivolol

Abstract

Electrochemical sensor based on carbon nanotubes decorated with zirconium oxide nanoparticles was developed for the determination of nebivolol at the potential of +1.05 V (vs. Ag/AgCl). Nanomaterials were dispersed in an anionic polymer and deposited by simple one-step casting method on glassy carbon electrode. Scanning electron microscopy and energy dispersive X-ray spectroscopy were used to study the surface morphology and structure characterization of deposited film. The sensor has a strongly improved sensitivity (9.29  10 -6 μA M -1 ). The electrocatalytical peak current of nebivolol shows a linear response from 100 nM to 10 mM with detection limit of 12 nM. Low-cost analysis of drug in serum samples was carried out after adsorption of nebivolol at the nanocomposite using differential pulse voltammetry. In comparison with HPLC method, the electrochemical method ensures faster and simpler quantification of nebivolol in pharmaceutical samples.

Hydrothermal implement with supporting of semiconductor ZrO2 (ZO), Ag doped ZrO2 (AZO) nanomaterial and its astrophysical, UV photocatalytic employment on Rh6G dye

“…10a-d) shows cyclic voltammetric of 1 μm of GCE and Ag-ZrO 2 with 0.01 scan rate in 0.1 N KCl solution. Cyclic voltammetric performance of just GCE electrode showed nearby no peaks location and reversible process formed (Subash et al 2013;Sadikovic and Nigovic 2017). Ag-ZrO 2 and ZrO 2 exhibit main oxidation peaks at Epa = 0.195 V i p = 2.050 e‾ 5A and Epa = 0.199 V, i p = 1.3000 e −6A , which match up to suitable oxidation process of transient Zr 4+ and Ag 2+ O 2− accessible in Ag-ZrO 2 nano particles, which is reduced at Epc = − 0.214 V and Epc = − 0.024 V) when examined for irreversible process (Liu et al 2016;Davar et al 2013).…”

Synthesis and Characterization of Zirconium Dioxide Anchored Carbon Nanofiber Composite for Enhanced Electrochemical Determination of Chloramphenicol in Food Samples

“…1,[5][6][7][10][11][12][13][14][15] Specifically, zirconium dioxide (ZrO 2 ) has shown excellent electrochemical and physiochemical properties such as low toxicity, high stability, biocompatibility, good electron transfers and surface charge properties. [16][17][18][19][20] For their extraordinary properties, ZrO 2 has emerged as a new promising platform for fuel cells, photocatalytic reactions, methanol oxidations, oxygen sensors, ceramic membranes and water-gas shift reaction. 21 Inspiringly, it can also serve as an excellent electrocatalyst with both oxidizing and reduction properties as well as in acidic and basic medium.…”