Development of dopamine-immunoreactive neurons associated with the antennal lobes of the honey bee,Apis mellifera

Kirchhof, B.S.; Homberg, Uwe; Mercer, Alison R.

doi:10.1002/(sici)1096-9861(19990906)411:4<643::aid-cne8>3.0.co;2-o

Cited by 24 publications

(12 citation statements)

References 67 publications

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“…Dopaminergic processes are widely distributed within the insect brain and dopamine has been found to be important in antennal lobe development in bees (Kirchhof et al 1999). It is possible that dopamine and other amines modulate olfaction as the brain develops and thus allow minor workers to discriminate among chemical cues associated with task performance in P. dentata.…”

Section: Discussionmentioning

confidence: 99%

Age-related changes in biogenic amines in individual brains of the ant Pheidole dentata

Seid

Traniello

2005

Naturwissenschaften

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The behavioral development of minor workers of the ant Pheidole dentata involves a progression of tasks beginning with brood care and culminating in foraging as individuals age. To understand the role of brain neurochemistry in age-related division of labor, we measured the levels of serotonin, dopamine and octopamine in individual brains of minor workers of different age. Serotonin and dopamine levels were significantly correlated with worker age: both increased as minor workers matured, and serotonin rose significantly in the oldest ants. In addition, the serotonin:dopamine ratio was significantly higher in the oldest workers. Octopamine levels did not change with age, although the ratios of octopamine:serotonin and octopamine:dopamine were significantly higher in the youngest workers. These age-associated changes in biogenic amine levels suggest an involvement of neuromodulators in minor worker behavioral ontogeny and temporal polyethism in P. dentata.

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Section: Discussionmentioning

confidence: 99%

Age-related changes in biogenic amines in individual brains of the ant Pheidole dentata

Seid

Traniello

2005

Naturwissenschaften

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“…Like histamine, the distribution of dopamine-like labeling has been mapped in the CNS of a variety of arthropods (e.g., Vieillemaringe et al 1984;Nässel et al 1988b;Schäfer and Rehder 1989;Milton et al 1991;Nässel and Elekes 1992;Wendt and Homberg 1992;Cournil et al 1994Cournil et al , 1995Lundell and Hirsh 1994;Schmidt and Ache 1994;Schürmann et al 1995;Bicker 1999;Hörner 1999;Kirchhof et al 1999;Monastirioti 1999;Wood and Derby 1996;Tierney et al 1999Tierney et al , 2003Mesce et al 2001;Pulver and Marder 2002;Pulver et al 2003;Fort et al 2004;Fu et al 2005;Hamasaka and Nässel 2006;Dickinson et al 2008). Here too, much of the labeling is reported to be centrally located, suggesting a role for dopamine as a locally released neuromodulator.…”

Section: Copepod Cns Contains Extensive Aminergic Innervationmentioning

confidence: 99%

Immunohistochemical mapping of histamine, dopamine, and serotonin in the central nervous system of the copepod Calanus finmarchicus (Crustacea; Maxillopoda; Copepoda)

Hartline

Christie

2010

Cell Tissue Res

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Calanoid copepods constitute an important group of marine planktonic crustaceans that often dominate the metazoan biomass of the world's oceans. In proportion to their ecological importance, little is known about their nervous systems. We have used immunohistochemical techniques in a common North Atlantic calanoid to localize re-identifiable neurons that putatively contain the biogenic amines histamine, dopamine, and serotonin. We have found low numbers of such cells and cell groups (approximately 37 histamine pairs, 22 dopamine pairs, and 12 serotonin pairs) compared with those in previously described crustaceans. These cells are concentrated in the anterior part of the central nervous system, the majority for each amine being located in the three neuromeres that constitute the brain (protocerebrum, deutocerebrum, and tritocerebrum). Extensive histamine labeling occurs in several small compact protocerebral neuropils, three pairs of larger, more posterior, paired, dense neuropils, and one paired diffuse tritocerebral neuropil. The most concentrated neuropil showing dopamine labeling lies in the putative deutocerebrum, associated with heavily labeled commissural connections between the two sides of the brain. The most prominent serotonin neuropil is present in the anterior medial part of the brain. Tracts of immunoreactive fibers of all three amines are prominent in the cephalic region of the nervous system, but some projections into the most posterior thoracic regions have also been noted.

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“…DA, OA and 5-HT are present in the brains of larvae, pupae and adult honeybees [53,68,81,83,106,175]. During the transition from larval to pupal stage, the levels of all three biogenic amines generally increase [175].…”

Section: Age-dependent Division Of Labourmentioning

confidence: 99%

Aminergic Control and Modulation of Honeybee Behaviour

Scheiner

Baumann²,

Blenau³

2006

140

109

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Biogenic amines are important messenger substances in the central nervous system and in peripheral organs of vertebrates and of invertebrates. The honeybee, Apis mellifera, is excellently suited to uncover the functions of biogenic amines in behaviour, because it has an extensive behavioural repertoire, with a number of biogenic amine receptors characterised in this insect.In the honeybee, the biogenic amines dopamine, octopamine, serotonin and tyramine modulate neuronal functions in various ways. Dopamine and serotonin are present in high concentrations in the bee brain, whereas octopamine and tyramine are less abundant. Octopamine is a key molecule for the control of honeybee behaviour. It generally has an arousing effect and leads to higher sensitivity for sensory inputs, better learning performance and increased foraging behaviour. Tyramine has been suggested to act antagonistically to octopamine, but only few experimental data are available for this amine. Dopamine and serotonin often have antagonistic or inhibitory effects as compared to octopamine.Biogenic amines bind to membrane receptors that primarily belong to the large gene-family of GTP-binding (G) protein coupled receptors. Receptor activation leads to transient changes in concentrations of intracellular second messengers such as cAMP, IP(3) and/or Ca(2+). Although several biogenic amine receptors from the honeybee have been cloned and characterised more recently, many genes still remain to be identified. The availability of the completely sequenced genome of Apis mellifera will contribute substantially to closing this gap.In this review, we will discuss the present knowledge on how biogenic amines and their receptor-mediated cellular responses modulate different behaviours of honeybees including learning processes and division of labour.

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Development of dopamine-immunoreactive neurons associated with the antennal lobes of the honey bee,Apis mellifera

Cited by 24 publications

References 67 publications

Age-related changes in biogenic amines in individual brains of the ant Pheidole dentata

Age-related changes in biogenic amines in individual brains of the ant Pheidole dentata

Immunohistochemical mapping of histamine, dopamine, and serotonin in the central nervous system of the copepod Calanus finmarchicus (Crustacea; Maxillopoda; Copepoda)

Aminergic Control and Modulation of Honeybee Behaviour

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