Development of controlled porosity polymer-ceramic composite scaffolds via fused deposition modeling

Kalita, Samar J.; Bose, Susmita; Hosick, Howard L.; Bandyopadhyay, Amit

doi:10.1016/s0928-4931(03)00052-3

Cited by 439 publications

(220 citation statements)

References 11 publications

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“…Bone tissue engineering via scaffolds involves development of a porous construct where cells are seeded in predefined biomechanical environment for cell growth and replacement of damaged tissues. A scaffold should essentially be porous (90% porosity) with well-connected pores of diameter 100-300 microns to allow diffusion of gases and transport of cellular fluids required to support cellular growth [5]. The porous architecture of the scaffold should withstand the mechanical loading to facilitate surgical handling during implantation.…”

Section: Introductionmentioning

confidence: 99%

Naturally derived biomaterials for development of composite bone scaffold: A review

Barua

Deoghare

Deb

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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E-mail: imon18enator@gmail.comAbstract. Over the last few decades, there has been an increasing demand of tissue engineered bone scaffolds as a substitute material for diseased or damaged bone segments. A variety of synthetic and natural biomaterials have been explored by researchers for development of composite scaffold. Naturally derived biomaterials have the advantages of immunomodulating, anti-toxic and biomimetic properties with the cellular environment in vivo, when compared to synthetic biomaterials. In this paper, different protein and polysaccharide based biomaterials used for developing composite bone scaffolds are reviewed. The properties of composite scaffolds developed from these biomaterials are highlighted. The study also includes different natural materials and biowastes which are used for deriving bioceramics for producing composite bone scaffolds. The overall study gives a brief idea on the importance of protein and polysaccharide based biomaterials and bioceramics for composite bone scaffold development and scope for future work in the field of naturally derived biomaterials.

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Section: Introductionmentioning

confidence: 99%

Naturally derived biomaterials for development of composite bone scaffold: A review

Barua

Deoghare

Deb

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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“…Recently, three-dimensional (3D) metal printing processes have been recognized as a flexible and rapid means of fabricating complex shapes such as implants and scaffolds, which are otherwise difficult to produce using conventional material processing techniques [5][6][7][8][9]. When Ti powder is used for 3D printing, it is best to use a spherical powder of approximately 100 μm diameter, in addition to having good powder flow, a tap density >65%, and low oxide content [11].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of a Spherical Titanium Powder by Combined Combustion Synthesis and DC Plasma Treatment

Choi

Ali

Hyun

et al. 2017

Archives of Metallurgy and Materials

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Combustion synthesis is capable of producing many types of refractory and ceramic materials, as well as metals, with a relatively lower cost and shorter time frame than other solid state synthetic techniques. TiO 2 with Mg as reductant were dry mixed and hand compacted into a 60 mm diameter mold and then combusted under an Ar atmosphere. Depending on the reaction parameters (Mg concentration 2 ≤ α ≤ 4), the thermocouples registered temperatures between 1160°C and 1710°C . 3 mol of Mg gave the optimum results with combustion temperature (T c ) and combustion velocity (U c ) values of 1372°C and 0.26 cm/s respectively. Furthermore, this ratio also had the lowest oxygen concentration in this study (0.8 wt%). After combustion, DC plasma treatment was carried out to spheroidize the Ti powder for use in 3D printing. The characterization of the final product was performed using X-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy, and N/O analysis.

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“…Currently, the most used 3D technologies for biological application include fused deposition modelling (FDM) 13 , selective laser sintering (SLS) 14 , inkjet printing 15 , laser direct writing (LDW) 16 , extrusion deposition technique 17 , pneumatic valve dispenser 18 , and so on. However, FDM and SLS require heating process at relatively high temperature, which does not apply to bioactive materials.…”

Section: Introductionmentioning

confidence: 99%

3D multi-nozzle system with dual drives highly potential for 3D complex scaffolds with multi-biomaterials

Chen

Zhang

Chen

et al. 2017

Int. J. Precis. Eng. Manuf.

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Development of controlled porosity polymer-ceramic composite scaffolds via fused deposition modeling

Cited by 439 publications

References 11 publications

Naturally derived biomaterials for development of composite bone scaffold: A review

Naturally derived biomaterials for development of composite bone scaffold: A review

Fabrication of a Spherical Titanium Powder by Combined Combustion Synthesis and DC Plasma Treatment

3D multi-nozzle system with dual drives highly potential for 3D complex scaffolds with multi-biomaterials

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