Development of CdSe–ZnO Flower-Rod Core-Shell Structure Based Photoelectrochemical Biosensor for Detection of Norovirous RNA

Han, Zhizhong; Weng, Qinghua; Lin, Chaofan; Yi, Jinquan; Kang, Jie

doi:10.3390/s18092980

Cited by 10 publications

(5 citation statements)

References 31 publications

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Section: Figurementioning

confidence: 99%

“…The ion-exchange method was used for CSZFR preparation and the assay benefits from advantages such as speed, simplicity, and convenience. The limit of detection of the assay was reported to be 0.50 nM, with a good linear relationship between the photocurrent and the NoV RNA density in the range of 0-5.10 nM [148]. In addition, of the electrochemical systems, the SPR biosensing method is the most common type of optical sensor for the detection of noroviruses.…”

Section: Norovirusmentioning

confidence: 99%

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Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors

et al. 2022

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Gastroenteritis, as one of the main worldwide health challenges, especially in children, leads to 3–6 million deaths annually and causes nearly 20% of the total deaths of children aged ˂5 years, of which ~1.5 million gastroenteritis deaths occur in developing nations. Viruses are the main causative agent (~70%) of gastroenteritis episodes and their specific and early diagnosis via laboratory assays is very helpful for having successful antiviral therapy and reduction in infection burden. Regarding this importance, the present literature is the first review of updated improvements in the employing of different types of biosensors such as electrochemical, optical, and piezoelectric for sensitive, simple, cheap, rapid, and specific diagnosis of human gastroenteritis viruses. The Introduction section is a general discussion about the importance of viral gastroenteritis, types of viruses that cause gastroenteritis, and reasons for the combination of conventional diagnostic tests with biosensors for fast detection of viruses associated with gastroenteritis. Following the current laboratory detection tests for human gastroenteritis viruses and their limitations (with subsections: Electron Microscope (EM), Cell Culture, Immunoassay, and Molecular Techniques), structural features and significant aspects of various biosensing methods are discussed in the Biosensor section. In the next sections, basic information on viruses causing gastroenteritis and recent developments for fabrication and testing of different biosensors for each virus detection are covered, and the prospect of future developments in designing different biosensing platforms for gastroenteritis virus detection is discussed in the Conclusion and Future Directions section as well.

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Section: Figurementioning

confidence: 99%

Section: Norovirusmentioning

confidence: 99%

Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors

et al. 2022

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“…The diffraction peaks related to the ZnO QDs were not observed in the XRD profile of ZT. Several reasons can account for the absence of the peaks: (1) The concentration of the ZnO QDs is low, where Han et al [23] reported a similar observation upon incorporation of CdSe QDs into the framework of ZnO flowers. (2) The effect may relate to the level of the homogeneity of the mixing of Ti and Zn components in ZT [24].…”

Section: X-ray Diffraction (Xrd) Analysismentioning

confidence: 99%

Floating ZnO QDs-Modified TiO2/LLDPE Hybrid Polymer Film for the Effective Photodegradation of Tetracycline under Fluorescent Light Irradiation: Synthesis and Characterisation

et al. 2021

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In this work, mesoporous TiO2-modified ZnO quantum dots (QDs) were immobilised on a linear low-density polyethylene (LLDPE) polymer using a solution casting method for the photodegradation of tetracycline (TC) antibiotics under fluorescent light irradiation. Various spectroscopic and microscopic techniques were used to investigate the physicochemical properties of the floating hybrid polymer film catalyst (8%-ZT@LLDPE). The highest removal (89.5%) of TC (40 mg/L) was achieved within 90 min at pH 9 due to enhanced water uptake by the LDDPE film and the surface roughness of the hybrid film. The formation of heterojunctions increased the separation of photogenerated electron-hole pairs. The QDs size-dependent quantum confinement effect leads to the displacement of the conduction band potential of ZnO QDs to more negative energy values than TiO2. The displacement generates more reactive species with higher oxidation ability. The highly stable film photocatalyst can be separated easily and can be repeatedly used up to 8 cycles without significant loss in the photocatalytic ability. The scavenging test indicates that the main species responsible for the photodegradation was O2●−. The proposed photodegradation mechanism of TC was demonstrated in further detail based on the intermediates detected by LC-time-of-flight/mass spectrometry (LC/TOF-MS).

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“…In these equations, , , and are the permittivity values of core, shell (of nanoparticle) and the surrounding medium, respectively. As stated before, the choice of = 3 reduces Equations ( 4)- (6) to the corresponding ordinary 3D space [40] forms.…”

Section: Model and Theorymentioning

confidence: 99%

“…More importantly, these find exciting applications in the biomedical area of research as the study includes targeted drug delivery, biosensing, bioimaging, targeted gene delivery, DNA interactions, pH nano-sensor for single cell, etc. [2][3][4][5][6][7]. In this stream, possible control over the plasmonic parameters led to the interest of the research and development community to explore varieties of electromagnetic features [8,9] of core-shell nanoparticles in different ambiance.…”

Section: Introductionmentioning

confidence: 99%

On the Core-Shell Nanoparticle in Fractional Dimensional Space

et al. 2020

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The investigation of core-shell nanoparticles has been greatly exciting in biomedical applications, as this remains of prime importance in targeted drug delivery, sensing, etc. In the present work, the polarizability and scattering features of nanoparticles comprised of nano-sized dielectric/metallic core-shell structures were investigated in the fractional dimensional (FD) space, which essentially relates to the confinement of charged particles. For this purpose, three different kinds of metals—namely aluminum, gold and silver—were considered to form the shell, having a common silicon dioxide (SiO2) nanoparticle as the core. It is noteworthy that the use of noble metal-SiO2 mediums interface remains ideal to realize surface plasmon resonance. The core-shell nanoparticles were considered to have dimensions smaller than the operating wavelength. Under such conditions, the analyses of polarizability and the scattering and absorption cross-sections, and also, the extinction coefficients were taken up under Rayleigh scattering mechanism, emphasizing the effects of a varying FD parameter. Apart from these, the tuning of resonance peaks and the magnitude of surface plasmons due to FD space parameter were also analyzed. It was found that the increase of FD space parameter generally results in blue-shifts in the resonance peaks. Apart from this, the usage of gold and silver shells brings in fairly large shifts in the peak positions of wavelengths, which allows them to be more suitable for a biosensing purpose.

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Development of CdSe–ZnO Flower-Rod Core-Shell Structure Based Photoelectrochemical Biosensor for Detection of Norovirous RNA

Cited by 10 publications

References 31 publications

Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors

Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors

Floating ZnO QDs-Modified TiO2/LLDPE Hybrid Polymer Film for the Effective Photodegradation of Tetracycline under Fluorescent Light Irradiation: Synthesis and Characterisation

On the Core-Shell Nanoparticle in Fractional Dimensional Space

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