Development of brushite particles synthesized in the presence of acidic monomers for dental applications

Chiari, Marina D.S.; Rodrigues, Marcela Charantola; Pinto, Mirella F.C.; Vieira, Douglas N.; Vichi, Flávio Maron; Vega, O.; Chrzanowski, Wojciech; Nagaoka, Noriyuki; Braga, Roberto Ruggiero

doi:10.1016/j.msec.2020.111178

Cited by 6 publications

(7 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The presence of a pendant, polymerizable, methacrylate group in MCP has the advantage of covalently attaching the MCP fillers to polymer resin composites by taking part in free-radical polymerization with vinyl- or methacrylate-functional co-monomers. This chemically modified reinforcement of calcium phosphate creates a more intimate contact with the resin phase, resulting in a dental material that can readily transfer its loads between its resin and filler phases [ 10 , 22 , 23 , 24 ]. The superior mechanical properties of the experimental composites with MCP were attributed to the better chemical integration of MCP with the resin phase.…”

Section: Discussionmentioning

confidence: 99%

“…These include (i) silane coupled HAp [ 18 ]; (ii) nano-sized amorphous calcium phosphate (NACP) [ 19 , 20 ]; and/or (iii) the functionalization of calcium phosphate particles with dimethacrylate monomers [ 21 , 22 ]. A modest improvement in fracture strength was observed in resin composites containing functionalized fillers in comparison to those containing non-functionalized brushite [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Experimental Dental Composites Containing a Novel Methacrylate-Functionalized Calcium Phosphate Component: Evaluation of Bioactivity and Physical Properties

Skaria¹,

Berk²

2021

Polymers

View full text Add to dashboard Cite

The aim of this study was to synthesize and characterize a novel methacrylate-functionalized calcium phosphate (MCP) to be used as a bioactive compound for innovative dental composites. The characterization was accomplished by attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). The incorporation of MCP as a bioactive filler in esthetic dental composite formulations and the ability of MCP containing dental composites to promote the precipitation of hydroxyapatite (HAp) on the surfaces of those dental composites was explored. The translucency parameter, depth of cure, degree of conversion, ion release profile, and other physical properties of the composites were studied with respect to the amount of MCP added to the composites. Composite with 3 wt.% MCP showed the highest flexural strength and translucency compared to the control composite and composites with 6 wt.% and 20 wt.% MCP. The progress of the surface precipitation of hydroxyapatite on the MCP containing dental composites was studied by systematically increasing the MCP content in the composite and the time of specimen storage in Dulbecco’s phosphate-buffered solution with calcium and magnesium. The results suggested that good bioactivity properties are exhibited by MCP containing composites. A direct correlation between the percentage of MCP in a composite formulation, the amount of time the specimen was stored in PBS, and the deposition of hydroxyapatite on the composite’s surface was observed.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Experimental Dental Composites Containing a Novel Methacrylate-Functionalized Calcium Phosphate Component: Evaluation of Bioactivity and Physical Properties

Skaria¹,

Berk²

2021

Polymers

View full text Add to dashboard Cite

show abstract

“…Silanization of DCPA particles significantly increased the material's fracture toughness; however, the released concentration of ions was reduced due to the hydrophobic character of the silane molecule 17 . Monomers containing carboxylic groups were tested in the functionalization of hydroxyapatite 18 and DCPD 19 particles. In both cases, materials containing particles functionalized with acrylic acid showed statistically higher fracture strength than materials with non‐functionalized particles after 24 h or 1 week.…”

Section: Introductionmentioning

confidence: 99%

“…However, after 60 days of storage in water there was no difference between materials containing functionalized and non-functionalized particles, suggesting that the interaction between carboxylic groups and calcium is unstable. 19 Triethylene glycol dimethacrylate (TEGDMA) has also been tested in the functionalization of CaP particles, resulting in increases in fracture strength of up to 32% compared to resin based composites with non-functionalized particles. [20][21][22] Equally favorable results were found when functionalization was performed with diethylene glycol dimethacrylate (DEGDMA).…”

mentioning

confidence: 99%

Influence of the calcium orthophosphate:glass ratio and calcium orthophosphate functionalization on the degree of conversion and mechanical properties of resin‐based composites

et al. 2022

View full text Add to dashboard Cite

The study verified the influence of calcium orthophosphate (CaP):glass ratio on the degree of conversion and mechanical properties of resin‐based composites containing either TEGDMA‐functionalized dicalcium phosphate anhydrous (DCPA) or non‐functionalized DCPA particles. The null hypotheses were that the evaluated variables are not affected by (1) CaP:glass ratio or (2) DCPA functionalization. DCPA particles were synthesized and half of them were functionalized with TEGDMA. Particle characterization included x‐ray diffraction, elemental analysis, laser scattering, helium picnometry and scanning electron microscopy. Two series of composites were prepared containing either DCPA‐NF (non‐functionalized) or DCPA‐F (functionalized), with total inorganic content of 50 vol % and DCPA:silanized barium glass (BG) ratios from 10:40 to 50:0. A composite containing 50 vol % BG was tested as control. DC was determined using FTIR spectroscopy. Biaxial flexural strength and modulus were tested after 24 h in water. Data were analyzed using Kruskal–Wallis/Dunn (flexural properties) or analysis of variance/Tukey tests (DC). Materials with similar actual DCPA contents were compared using Student's t test (alpha: 0.05). DC was higher for materials with DCPA‐F, except for the 10:40 ratio. DCPA‐F resulted in higher strength than DCPA‐NF only at 40:10 ratio. Modulus was not affected by functionalization. Materials with similar actual DCPA contents showed differences in DC (F > NF), while no difference in flexural properties was observed between materials with 28%–30% DCPA. Both null hypotheses were rejected.

show abstract

“…These include (i) silane coupled HAp [18]; (ii) nano-sized amorphous calcium phosphate (NACP) [19,20]; and or (iii) the functionalization of calcium phosphate particles with dimethacrylate monomers [21,22]. Modest improvement in fracture strength was observed in resin composites containing functionalized fillers in comparison to those containing non-functionalized brushite [23].…”

Section: Introductionmentioning

confidence: 99%

Experimental Dental Composites Containing a Novel Methacrylate-Functionalized Calcium Phosphate Component: Evaluation of Bioactivity and Physical Properties

Skaria¹,

Berk²

2021

Preprint

View full text Add to dashboard Cite

The aim of this study was to synthesize and characterize a novel Methacrylate- functionalized Calcium Phosphate (MCP) used as a bioactive compound for innovative dental composites. The characterization was accomplished by Attenuated Total Reflectance Fourier-Transform Infrared Spectroscopy (ATR-FTIR), X-Ray Diffraction Analysis (XRDA), Scanning Electron Microscopy (SEM), and EnergyDispersive Spectroscopy (EDS). The incorporation of MCP as a bioactive filler in esthetic dental composite formulations and the ability of MCP containing dental composites to promote precipitation of hydroxyapatite (HAp) on the surfaces of those dental composites was explored. The translucency parameter, depth of cure, degree of conversion, ion release profile, and other physical properties of composites were studied with respect to the amount of MCP added to the composites. Composites containing 3 Wt.%, 6 Wt.%, and 20 Wt.% MCP were evaluated at 7, 14, and 21 days. The progress of surface precipitation of hydroxyapatite on MCP-containing dental composites was studied by systematically increasing the MCP content in the composite and the time of specimen storage in Dulbecco’s phosphate-buffered solution with calcium and magnesium. It was found that there was a direct correlation between the percentage of MCP in a composite formulation, the amount of time the specimen was stored in PBS, and the deposition of hydroxyapatite on the composite’s surface

show abstract

Development of brushite particles synthesized in the presence of acidic monomers for dental applications

Cited by 6 publications

References 38 publications

Experimental Dental Composites Containing a Novel Methacrylate-Functionalized Calcium Phosphate Component: Evaluation of Bioactivity and Physical Properties

Experimental Dental Composites Containing a Novel Methacrylate-Functionalized Calcium Phosphate Component: Evaluation of Bioactivity and Physical Properties

Influence of the calcium orthophosphate:glass ratio and calcium orthophosphate functionalization on the degree of conversion and mechanical properties of resin‐based composites

Experimental Dental Composites Containing a Novel Methacrylate-Functionalized Calcium Phosphate Component: Evaluation of Bioactivity and Physical Properties

Contact Info

Product

Resources

About