Development of Biosensors From Biopolymer Composites

Sawant, Shilpa N.

doi:10.1016/b978-0-12-809261-3.00013-9

Cited by 73 publications

(52 citation statements)

References 86 publications

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“…Thermal biosensors are based on measurement of the thermal changes occurring on biochemical recognition. Piezoelectric biosensors involve the measurement of mass change occurring as a result of biomolecular interaction [25]. Receptors of molecules that have affinity for the proteins and DNA analysed are "constructed" on the surface of nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Methods of Gold and Silver Nanoparticles Preparation

et al. 2019

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The versatile family of nanoparticles is considered to have a huge impact on the different fields of materials research, mostly nanoelectronics, catalytic chemistry and in study of cytocompatibility, targeted drug delivery and tissue engineering. Different approaches for nanoparticle preparation have been developed, not only based on “bottom up” and “top down” techniques, but also several procedures of effective nanoparticle modifications have been successfully used. This paper is focused on different techniques of nanoparticles’ preparation, with primary focus on metal nanoparticles. Dispergation methods such as laser ablation and vacuum sputtering are introduced. Condensation methods such as reduction with sodium citrate, the Brust–Schiffrin method and approaches based on ultraviolet light or biosynthesis of silver and gold are also discussed. Basic properties of colloidal solutions are described. Also a historical overview of nanoparticles are briefly introduced together with short introduction to specific properties of nanoparticles and their solutions.

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Section: Introductionmentioning

confidence: 99%

Methods of Gold and Silver Nanoparticles Preparation

et al. 2019

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“…• Based on the sensing mechanism: Based on the sensing mechanisms, biosensors can be of various types. The most common among them are [46], [47]:…”

Section: ) Classifications Of Biosensorsmentioning

confidence: 99%

Advancing Modern Healthcare With Nanotechnology, Nanobiosensors, and Internet of Nano Things: Taxonomies, Applications, Architecture, and Challenges

Pramanik

Solanki

Debnath³

et al. 2020

IEEE Access

102

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Healthcare sector is probably the most benefited from the applications of nanotechnology. The nanotechnology, in the forms of nanomedicine, nanoimplants, nanobiosensors along with the internet of nano things (IoNT), has the potential to bring a revolutionizing advancement in the field of medicine and healthcare services. The primary aim of this paper is to explore the clinical and medical possibilities of these different implementations of nanotechnology. This paper provides a comprehensive overview of nanotechnology, biosensors, nanobiosensors, and IoNT. Furthermore, multilevel taxonomies of nanotechnology, nanoparticles, biosensors, nanobiosensors, and nanozymes are presented. The potential medical and clinical applications of these technologies are discussed in details with several examples. This paper specifically focuses on IoNT and its role in healthcare. In addition to describing a general architecture of IoNT for healthcare, the communication architecture of the IoNT is also explained. The challenges in the successful realization of IoNT are also discussed critically, along with a special discussion on internet of bio-nano things (IoBNT) and its potential in making IoNT more compatible to human body.

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“…A biosensor is defined by IUPAC as an integrated transducer-receptor device, which combines a biological recognition element with a transducer capable of converting the biological response into quantitative or semi-quantitative analytical information [20,21]. Accordingly, biosensors can be classified in terms of their biological recognition elements and transduction principle [21][22][23]. Immunosensors and DNA sensors are affinity ligand-based biosensing devices that involve the transduction of immunochemical reactions benefiting from the highly specific interaction between antibody-antigen and DNA strands, respectively [21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

“…Accordingly, biosensors can be classified in terms of their biological recognition elements and transduction principle [21][22][23]. Immunosensors and DNA sensors are affinity ligand-based biosensing devices that involve the transduction of immunochemical reactions benefiting from the highly specific interaction between antibody-antigen and DNA strands, respectively [21][22][23][24][25]. Development of biosensors with high sensitivity through the enhancement of their active surface area, (electro)chemical activity and conductivity or optical properties is one of the major challenges of the biosensing field [21,[25][26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Nanomaterials towards Biosensing of Alzheimer’s Disease Biomarkers

2019

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Alzheimer’s disease (AD) is an incurable and highly debilitating condition characterized by the progressive degeneration and/or death of nerve cells, which leads to manifestation of disabilities in cognitive functioning. In recent years, the development of biosensors for determination of AD’s main biomarkers has made remarkable progress, particularly based on the tremendous advances in nanoscience and nanotechnology. The unique and outstanding properties of nanomaterials (such as graphene, carbon nanotubes, gold, silver and magnetic nanoparticles, polymers and quantum dots) have been contributing to enhance the electrochemical and optical behavior of transducers while offering a suitable matrix for the immobilization of biological recognition elements. Therefore, optical and electrochemical immuno- and DNA-biosensors with higher sensitivity, selectivity and longer stability have been reported. Nevertheless, strategies based on the detection of multiple analytes still need to be improved, as they will play a crucial role in minimizing misdiagnosis. This review aims to provide insights into the conjugation of nanomaterials with different transducers highlighting their crucial role in the construction of biosensors for detection of AD main biomarkers.

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Development of Biosensors From Biopolymer Composites

Cited by 73 publications

References 86 publications

Methods of Gold and Silver Nanoparticles Preparation

Methods of Gold and Silver Nanoparticles Preparation

Advancing Modern Healthcare With Nanotechnology, Nanobiosensors, and Internet of Nano Things: Taxonomies, Applications, Architecture, and Challenges

Nanomaterials towards Biosensing of Alzheimer’s Disease Biomarkers

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