Development of biomimetic in vitro fatigue assessment for UHMWPE implant materials

Porous Ultrahigh Molecular Weight Polyethylene/Functionalized Activated Nanocarbon Composites with Improved Biocompatibility

“…Porous permeation is one of the most important characteristics in natural articular cartilage models. A low P v value can easily lead to poor fluid flow in cartilage, but a high P v value can easily lead to cartilage brittleness, resulting in fractures, cartilage loss, and other diseases [ 10 , 11 , 12 ]. For health reasons, the P v values of cartilaginous materials should be as close as possible to that of natural cartilage, which must be between 30% and 47% [ 15 , 16 , 37 , 38 ].…”

“…The latest technologies in the field of joint replacement include bone integration of artificial joints, improvements in bone replacement materials, implants, and rehabilitation devices, and joint replacement technology based on dynamic bone synthesis models [ 5 , 6 ]. New bone materials, such as PVA-H [ 7 , 8 , 9 ] and UHMWPE, with a high modulus of elasticity, biocompatibility, and mechanical properties, were studied systematically and in depth [ 10 , 11 , 12 ]. Ultra-high molecular weight polyethylene (UHMWPE) is the most common material used for the artificial joint bearing component, with the advantage of unique characteristics and favorable properties, such as biocompatibility, chemical stability, high wear resistance, and low friction [ 10 , 11 , 12 , 13 , 14 ].…”

“…New bone materials, such as PVA-H [ 7 , 8 , 9 ] and UHMWPE, with a high modulus of elasticity, biocompatibility, and mechanical properties, were studied systematically and in depth [ 10 , 11 , 12 ]. Ultra-high molecular weight polyethylene (UHMWPE) is the most common material used for the artificial joint bearing component, with the advantage of unique characteristics and favorable properties, such as biocompatibility, chemical stability, high wear resistance, and low friction [ 10 , 11 , 12 , 13 , 14 ]. However, the low hydrophilicity and mechanics properties of UHMWPE easily lead to artificial joint replacement failure [ 15 , 16 ].…”

Mechanical in vitro fatigue testing of implant materials and components using advanced characterization techniques

“…In the following, selected experimental results regarding the fatigue behavior of UHMWPE are highlighted to demonstrate the reliability of the in vitro short‐time testing method proposed. The complete experimental results were published in References 64,65.…”

“…(A) Experimental set‐up for in vitro experiments with UHMWPE; 64 (B) exemplary result of a multiple amplitude test on UHMWPE in a simulated body fluid at 37°C 65 . UHMWPE, ultra‐high molecular weight polyethylene…”