Development of bile duct cancer in a 26-year-old man after resection of infantile choledochal cyst

Long-term outcomes after hepaticojejunostomy for choledochal cyst: a 10- to 27-year follow-up

“…One patient developed multiple intrahepatic bile duct stones and underwent repeated lithotripsy with a percutaneus transhepatic cholangioscope. Thereafter, he developed cholangiocarcinoma some 26 years after his initial surgery (this has been reported previously in greater detail [11]). …”

“…In 1969, Babbitt [1] reported an AAPBD in 3 children with CCs, in which he proposed that is was the cause of the dilatation. The combination is widely held to be a risk factor for biliary tract malignancy [2], and several investigators have reported cholangiocarcinoma developing in patients younger than 20 years [3][4][5][6][7][8][9] and others have shown carcinoma arising from the intrahepatic bile duct or residual common bile duct following resection of their CC [10,11]. Nonetheless, most patients with CC have a good prognosis when diagnosed and treated early.…”

Intrahepatic cholangiocarcinoma with intrahepatic biliary lithiasis arising 47 years after the excision of a congenital biliary dilatation: Report of a case

“…Three died of the disease before hepatectomy. Although Ono et al previously reported one case of multiple peripheral lithiases secondary to generation of ICC (20), the current report is the first case of ICC with intrahepatic biliary lithiasis in the opposite lobe arising after the excision of CBD to our knowledge. In the former case hemihepatectomy with re-reconstruction by hepaticojejunostomy was successfully performed, while in the present patient, the ICC was not resected because of the appearance of hepatic insufficiency in the future remnant liver volume and biliary lithiasis.…”

Diagnosis and treatment of pancreaticobiliary maljunction in children

“…4 On the other hand, several reports have shown carcinoma arising from the intrahepatic bile duct or residual common bile duct after resection of choledochal cysts. 45,46 Therefore, successive follow-up is needed for patients who undergo total resection of a choledochal cyst with PBM, especially for patients with some complications, such as biliary stones or stenosis of the intrahepatic bile duct. 44 From the point of view of convenience and reliability, a combination of ultrasonography and CT scans once per year on an outpatient basis is therefore considered to be suitable for successive follow-up in children with PBM after surgery.…”