Development of Atopic Dermatitis During the First 3 Years of Life

Halkjær, Liselotte Brydensholt; Loland, Lotte; Buchvald, Frederik; Agner, Tove; Skov, Lone; Strand, Matthew; Bisgaard, Hans

doi:10.1001/archderm.142.5.561

Cited by 102 publications

(38 citation statements)

References 30 publications

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“…For better understanding among Swedish parents, we enquired about a ‘red rash' instead of ‘chronic relapsing dermatitis' which occurs in the ISAAC questionnaire, and we asked about itch in a separate question. Furthermore, the list of involved sites was extended, since more sites can be involved in younger children [16]. Thus, the written parental CEQ had three key questions: (1) Does your child have or has your child had a red rash/eczema which can come and go ?…”

Section: Methodsmentioning

confidence: 99%

Validation of a Parental Questionnaire to Identify Atopic Dermatitis in a Population-Based Sample of Children up to 2 Years of Age

et al. 2013

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Background: Validated eczema questionnaires have been available for schoolchildren only, but the incidence of atopic dermatitis (AD) is highest during infancy. Objective: To validate a parental questionnaire to identify AD in children up to 2 years of age. Methods: Parents of 476 children answered a written questionnaire prior to an examination by a physician. Sensitivity, specificity, predictive values and test-retest reliability of the questionnaire were assessed. Results: A total of 245 (51%) girls and 231 (49%) boys, aged 1-24 months, with and without physician-diagnosed AD participated. Seventy-one children (15%) had physician-diagnosed AD. Validation of the questionnaire by comparisons with physicians' diagnoses showed a sensitivity of 0.87 (95% confidence interval, CI, 0.77-0.94) and a specificity of 0.98 (95% CI, 0.96-0.99). The positive predictive value was 0.90 (95% CI, 0.80-0.96) and the negative predictive value was 0.98 (95% CI, 0.96-0.99). Conclusion: The questionnaire identified AD in children aged 0-2 years with high accuracy.

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Section: Methodsmentioning

confidence: 99%

Validation of a Parental Questionnaire to Identify Atopic Dermatitis in a Population-Based Sample of Children up to 2 Years of Age

et al. 2013

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“…178 Thus, there is an urgent need for a standardised definition of an incident case of eczema that offers a satisfactory trade-off between overinclusion of transient eczematous eruptions of irritant and other aetiologies and overexclusion of genuine milder short-lived forms of eczema that still represent a health-care problem.…”

Section: Eczema Prevention Work Programmementioning

confidence: 99%

“…We propose the following definition, based on empirical reasoning considering the requirements of such a definition, and informed by previous studies that signal the best markers of true eczema. 178 A history of an itchy skin condition, which is either continuous or intermittent, lasting at least 4 weeks, plus three or more of the following:…”

Section: Proposed Solutionmentioning

confidence: 99%

“…Another benefit of this proposed definition is that it does not allow a definition of eczema to be made based on the presence of facial eczema alone. Halkjaer et al 178 found that 40% of children with facial eczema do not eventuate into chronic eczema. Finally, this definition allows for early treatment intervention during the course of a prospective study and does not require the disease to be untreated for a full 4 weeks if anti-inflammatory therapy is needed.…”

Section: Proposed Solutionmentioning

confidence: 99%

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A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease

Kim

Batchelor

Bath‐Hextall

et al. 2016

Programme Grants Appl Res

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Programme Grants for Applied ResearchISSN 2050-4322 (Print) ISSN 2050-4330 (Online) This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full PGfAR archive is freely available to view online at www.journalslibrary.nihr.ac.uk/pgfar. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Programme Grants for Applied Research journalReports are published in Programme Grants for Applied Research (PGfAR) if (1) they have resulted from work for the PGfAR programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors. Programme Grants for Applied Research programmeThe Programme Grants for Applied Research (PGfAR) programme, part of the National Institute for Health Research (NIHR), was set up in 2006 to produce independent research findings that will have practical application for the benefit of patients and the NHS in the relatively near future. The Programme is managed by the NIHR Central Commissioning Facility (CCF) with strategic input from the Programme Director.The programme is a national response mode funding scheme that aims to provide evidence to improve health outcomes in England through promotion of health, prevention of ill health, and optimal disease management (including safety and quality), with particular emphasis on conditions causing significant disease burden.For more information about the PGfAR programme please visit the website: http://www.nihr.ac.uk/funding/programme-grants-forapplied-research.htm This reportThe research reported in this issue of the journal was funded by PGfAR as project number RP-PG-0407-10177. The contractual start date was in September 2008. The final report began editorial review in April 2014 and was accepted for publication in April 2016. As the funder, the PGfAR programme agreed the research questions and study designs in advance with the investigators. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The PGfAR editors and production house have tried to ensure the accuracy of the authors' report and would like to thank the reviewers for their constructive comments on the final report document. However, they do not accept liability for damages or losses arising from material published in this report.This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, CCF, NETSCC, PGfAR or the Department of Health. If there are verbatim quotations included in this publication the views and opinions expressed by the interviewees are those of the interviewees and do not necessarily reflect those of the authors, those of the NHS, the NIHR, ...

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“…Üç yaşına dek kümülatif AD insidansı %44 olarak belirlenirken, deri tutulumunun, saçlı deri, alın, kulak ve boynu içine alan bölgede başladığı; daha sonra ise ekstensör alanlara ve gövdeye yayıldığı bildirilmiştir ("kar maskesi benzeri dağılım"). Bu çalışmada, AD gelişimi yönünden en yüksek prediktif değerin ise, kol ve eklemlerde ekzema varlığında saptandığı bildirilmektedir 13 . Çocukluk dönemindeki AD, simetrik, düzensiz sınırlı, eritematöz papüller, ekskoryasyonlar, krutlanma ve likenifikasyon ile kendini gösterir.…”

Section: Klinik Bulgular Ve Tanı öLçütleriunclassified

Atopic Dermatitis in Children

Taşkapan¹

2011

Turkderm

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ÖzetAtopik dermatit (AD), prevalansı giderek artan, küçük çocukların %10-20'sini etkileyen ve en sık görülen deri hastalıklarından biridir. Hastalık, sıklıkla solunum yolu ve besin allerjileriyle birliktelik gösterir; kaşıntılı, sık nüks eden, kronik inflamatuar bir nitelik taşır. Bu yazıda infantil ve çocukluk dönemindeki AD'nin epidemiyolojisi, gelişimindeki risk etmenleri, klinik bulguları, tanı ölçütleri, ayırıcı tanı ve tedavi yaklaşımları, güncel bilimsel verilerin ışığında özetlenmektedir.

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Development of Atopic Dermatitis During the First 3 Years of Life

Cited by 102 publications

References 30 publications

Validation of a Parental Questionnaire to Identify Atopic Dermatitis in a Population-Based Sample of Children up to 2 Years of Age

Validation of a Parental Questionnaire to Identify Atopic Dermatitis in a Population-Based Sample of Children up to 2 Years of Age

A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease

Atopic Dermatitis in Children

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