Development of an optimized LSO/LuYAP phoswich detector head for the Lausanne ClearPET demonstrator

Mosset, J.-B.; Devroede, O.; Krieguer, M.; Rey, M.; Vieira, J.-M.; Jung, Jaeho; Kuntner, Claudia; Streun, M.; Ziemons, K.; Auffray, E.; Sempere-Roldan, P.; Lecoq, P.; Bruyndonckx, Peter; Loude, J.-F.; Tavernier, S.; Morel, C.

doi:10.1109/tns.2005.862958

Cited by 29 publications

(15 citation statements)

References 23 publications

(17 reference statements)

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“…The results also indicate the 8 layers of crystals provide superior performance to a 2 layer or 4 layer phoswich devices with smaller ring diameters [3] [14][15] [16].…”

Section: Resultsmentioning

confidence: 99%

Spatial resolution of a small cubic LYSO scintillator crystal detector with depth-of-interaction capabilities in a small animal PET scanner

Perera

Lerch

Rosenfeld

et al. 2007

2007 IEEE Nuclear Science Symposium Conference Record

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Abstract-Present Positron Emission Tomography (PET) detectors suffer from degradation of the spatial resolution due to the lack of depth-of-interaction (DOI) information leading to uncertainty in deducing the Lines of Response (LOR) between coincident events. The Centre for Medical Radiation Physics at the University of Wollongong has developed a novel detector module which will provide depth of interaction information while retaining the sensitivity of current scanners. This will result in superior imaging together with the ability to locate smaller lesions. This work focuses on preliminary investigations of the suitability of replacing the bulky scintillator crystals and photomultiplier tubes of traditional PET detector modules with compact 3 × 3 × 3 mm 3 LYSO scintillator crystals individually coupled to Si photdetectors.The simulations were undertaken using GATE, a high level front end for GEANT4, specifically designed for use in the simulation of PET and SPECT. The simulation results quantify the level of improvement that can be potentially gained using a new detector module capable of providing a uniform spatial resolution across the entire field of view (FOV). Data is analysed using a newly developed sinogram binning technique. Simulation results show a resolution of 1.6 mm FWHM can be obtained for the entire FOV of this scanner (approximately 230 mm). This represents an improvement of approximately 75% in the resolution at the edges of field of view compared to traditional detector module design. Comparison of spatial resolution data for the novel detector module and phoswich detectors is also presented

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“…The results also indicate the 8 layers of crystals provide superior performance to a 2 layer or 4 layer phoswich devices with smaller ring diameters [3] [14][15] [16].…”

Section: Resultsmentioning

confidence: 99%

Spatial resolution of a small cubic LYSO scintillator crystal detector with depth-of-interaction capabilities in a small animal PET scanner

Perera

Lerch

Rosenfeld

et al. 2007

2007 IEEE Nuclear Science Symposium Conference Record

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“…The ClearPET main characteristics are its detectors constituted of LSO/LuYAP phoswich crystal matrices read-out by multi-anode photomultiplier tubes and its partial ring geometry, which allows for inserting an X-ray tube and the hybrid pixel camera which together constitute a micro-CT scanner [38,47]. Both modalities can therefore share the same field of view.…”

Section: The Clearpet/xpad Demonstratormentioning

confidence: 99%

Some proximal methods for Poisson intensity CBCT and PET

Anthoine¹,

Aujol²,

Boursier³

et al. 2012

Inverse Problems &Amp; Imaging

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Cone-Beam Computerized Tomography (CBCT) and Positron Emission Tomography (PET) are two complementary medical imaging modalities providing respectively anatomic and metabolic information of a patient. In the context of public health, one must address the problem of dose reduction of the potentially harmful quantities related to each exam protocol : X-rays for CBCT and radiotracer for PET. Two demonstrators based on a technological breakthrough (acquisition devices work in photon-counting mode) have been developed and we investigate in this paper the two related tomographic reconstruction problems. We formulate separately the CBCT and the PET problems in two general frameworks that encompass the physics of the acquisition devices and the specific discretization of the object to reconstruct. These objects may be observed from a limited number of angles of views and we take into account the specificity of the Poisson noise. We propose various fast numerical schemes based on proximal methods to compute the solution of each problem. In particular, we show that primal-dual approaches are well suited in the PET case when considering non differentiable regularizations such as Total Variation. Experiments on numerical simulations and real data are in favor of the proposed algorithms when compared with the well-established methods.

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“…The ideal scintillator should have the following advantages: high density, high effective atomic number, high light yield, short light decay time, and good energy resolution, etc. Many kinds of scintillation crystals have been used in PET detectors, including thallium doped with sodium iodide (NaI(Tl)), bismuth germanate (BGO), gadolinium oxyorthosilicate (GSO), lutetium oxyorthosilicate (LSO), lutetium-yttrium oxyorthosilicate (LYSO), and lanthanum [3][4][5][6]. Among these scintillators, LYSO has been the first choice in state-of-the-art PET detector design, especially in TOF-PET imaging applications.…”

Section: Introductionmentioning

confidence: 99%

Positron emission tomography detector performance with different crystal pitches

Tong

Fan

Dong

et al. 2017

Radiat Detect Technol Methods

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Aims: In this work, we evaluated the performance of three pitches positron emission tomography (PET) detectors for building a high-resolution small-animal PET imaging experimental platform. Methods: The evaluation of PET detectors includes twodimensional crystal identification, energy resolution, and crystal look-up table. The nuclear instrumentation module and PXI data acquisition (DAQ) system were both used to obtain flood images. The energy spectrum of the Na-22 source was measured. PET detectors of 2.0 and 1.6 mm pitches used in our present experiment were composed of lutetium yttrium oxyorthosilicate (LYSO) crystals directly coupled to position-sensitive photomultiplier tubes (PSPMTs). The 1.3-mm pitch detector comprises a LYSO crystal, a tapered light-guide, and a PSPMT. The crystal sizes of the detectors were a 10 × 10 array of 2.0 × 2.0 × 10 mm 3 crystals, a 10 × 10 array of 1.6 × 1.6 × 10 mm 3 crystals, and an 18×18 array of 1.3×1.3×10 mm 3 crystals, respectively. Due to the lower sampling frequency of the DAQ system, a spline interpolation algorithm was introduced in the signal waveform to reconstruct the peak values. Results: The experimental results indicated that all three PET detector crystals could be clearly identified. A detailed analysis demonstrated that the key characteristic full width at half maximum (FWHM) values of the crystals profile could reach 0.46 ± 0.03, 0.32 ± 0.03, and 0.21 ± 0.02 mm, while the crystal average energy resolutions were 16.8% ± 1.76%, 20.1% ± 2.24%, and 31.5% ± 3.76%, which correspond to B YongZhi Yin yinyzh@lzu.edu.cn 1 School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China pitches of 2.0-, 1.6-, and 1.3-mm, respectively. Conclusions: The PET detector modules of LYSO crystal arrays could be potentially used in the small-animal PET imaging applications and are promising to achieve submillimeter PET images.

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Development of an optimized LSO/LuYAP phoswich detector head for the Lausanne ClearPET demonstrator

Cited by 29 publications

References 23 publications

Spatial resolution of a small cubic LYSO scintillator crystal detector with depth-of-interaction capabilities in a small animal PET scanner

Spatial resolution of a small cubic LYSO scintillator crystal detector with depth-of-interaction capabilities in a small animal PET scanner

Some proximal methods for Poisson intensity CBCT and PET

Positron emission tomography detector performance with different crystal pitches

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