Development of an optical sensor based on surface plasmon resonance phenomenon for diagnosis of dengue virus E-protein

Recent Developments in Nanotechnology for Detection and Control of Aedes aegypti-Borne Diseases

“…This protein can be detected earlier, at the start of the immune system response to the infection (Omar et al, 2018). Figure 4 shows the schematic immobilization of IgM in gold/Fe-MPA-NCCCTAB (3-mercaptopropionicacid nanocellulose crystalline/hexadecyltrimethylammonium bromide, respectively)/EDC-N-hydroxysuccinimide (NHS) for early detection of dengue virus E-protein using surface plasmon resonance explored by Omar et al (2018). By introducing IgM immobilized Fe-MPA-NCC-CTAB/EDC-NHS on a gold surface, it is possible to determine the E-protein concentration in a range of 0.0001-10 nM.…”

“…However, as mentioned previously, it is very important to be able to achieve early detection of arbovirus infection but the biosensors had generally been designed to detect NS-type proteins that are only produced from the fifth day of infection onwards (Nawaz et al, 2018). Omar et al (2018) overcame this limitation by designing an optical sensor based on the surface plasmon resonance phenomenon, which was applied to the diagnosis of dengue virus structural E-protein that forms the coat of the host virus itself. This protein can be detected earlier, at the start of the immune system response to the infection (Omar et al, 2018).…”

“…Omar et al (2018) overcame this limitation by designing an optical sensor based on the surface plasmon resonance phenomenon, which was applied to the diagnosis of dengue virus structural E-protein that forms the coat of the host virus itself. This protein can be detected earlier, at the start of the immune system response to the infection (Omar et al, 2018). Figure 4 shows the schematic immobilization of IgM in gold/Fe-MPA-NCCCTAB (3-mercaptopropionicacid nanocellulose crystalline/hexadecyltrimethylammonium bromide, respectively)/EDC-N-hydroxysuccinimide (NHS) for early detection of dengue virus E-protein using surface plasmon resonance explored by Omar et al (2018).…”

“…By introducing IgM immobilized Fe-MPA-NCC-CTAB/EDC-NHS on a gold surface, it is possible to determine the E-protein concentration in a range of 0.0001-10 nM. The sensitivity found by optical sensor in contact with DENV is 39.96 • nM −1 (Omar et al, 2018). Vinayagam et al (2018) reported the recognition of serotype-specific DENV employing multicolor triangular silver nanoparticles (TAg), which has the potential to be a powerful diagnosis technique that is able to differentiate between various serotypes.…”

Optical Studies of Graphene Oxide/Poly(amidoamine) Dendrimer Composite Thin Film and Its Potential for Sensing Hg2+ Using Surface Plasmon Resonance Spectroscopy

“…The reflected He-Ne beam laser was detected by a sensitive photodiode and then processed with a lock-in-amplifier (SR 530). (32)(33)(34)(35)(36)…”