Development of an Open Metadata Schema for Prospective Clinical Research (openPCR) in China

Abstract

OpenPCR is an open metadata schema based on research registration standards, standards of the Clinical Data Interchange Standards Consortium (CDISC) and Chinese healthcare related standards, and is to be publicly available throughout China. It considers future integration of EHR and CR by adopting data structure and data terms in Chinese EHR Standard. Archetypes in openPCR are modularity models and can be separated, recombined, and reused. The authors recommend that the method to develop openPCR can be referenced by other countries when designing metadata schema of clinical research. In the next steps, openPCR should be used in a number of CR projects to test its applicability and to continuously improve its coverage. Besides, metadata schema for research protocol can be developed to structurize and standardize protocol, and syntactical interoperability of openPCR with other related standards can be considered.

Construction of a Meta-Evidence Prototype Database of Traditional Chinese Medicine Splenogastric Diseases and Its Application in an Automatic Meta-Analysis System

“…A typical application of this system starts from clinical problem (i.e., PICO) querying, matched RCTs (meta-evidence in this system) complete meta-analysis, and a systematic review in the background; In recent years, there have been many studies on automatic SRs assisted by computer [24], but most of them still adopt the semi-automatic method of "human-machine combination" [25]. Some meta-evidence similar data researches, such as the CISMeF metadata project, based on the Dublin core model, could describe the metadata of EBM resources [26], and Xu et al [27] established an evidencebased medicine metadata experiment database. Another study [28] reported a web scraping algorithm developed by python language that can automatically extract metadata of published literature (such as title, abstract, keywords, year, author, and DOI).…”

Accessing and sharing health information for post-discharge stroke care through a national health information exchange platform - a case study

“…In practice, there are existing experiences of standards implementation that have succeeded to provide access to clinical and health related information within a region e.g. Lombardy region in Italy [20] and openEHR implementation in Chinese hospitals [21, 22]. Yet, interoperability of HIS remains a problem in most healthcare systems and was identified as still being a major issue for usability of eHealth in Sweden in a study from 2013 [23].…”