Development of an integrated detector for NMR microscopy

Stocker, J.E.; Peck, Timothy L.; Franke, S.J.; Kruse, J.; Feng, Milton; Magin, Richard L.

doi:10.1109/iembs.1995.575391

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…Micro-fabrication opens the perspective of direct integration of the MR detector with the receiver electronics. Planar micro-coils have been fabricated directly on GaAs substrates, [67][68][69] in combination with a metal semiconductor field effect transistor (MESFET) amplifier, and electroplated Cu coils have been integrated with a CMOS amplifier circuit. 83 This work was later extended to a fully integrated probe on a 10 mm 2 silicon chip containing planar spiral coils, a radio-frequency preamplifier, a mixer, and an audio-frequency amplifier.…”

Section: Micro-coils Integrated With Micro-electronicsmentioning

confidence: 99%

Microscale nuclear magnetic resonance: a tool for soft matter research

et al. 2012

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Nuclear magnetic resonance spectroscopy (NMR) and imaging (MRI) are important non-destructive investigative techniques for soft matter research. Continuous advancements have not only lead to more sensitive detection, and new applications, but have also enabled the shrinking of the detectable volume of sample, and a reduction in time needed to acquire a spectrum or image. At the same time, advances in microstructuring and on-chip laboratories have also continued unabated. In recent years these two broad areas have been productively joined into what we term micro nuclear magnetic resonance (mMR), an exciting development that includes miniaturized detectors and hyphenation with other laboratory techniques, for it opens up a range of new possibilities for the soft matter scientist. In this paper we review the available miniaturization technologies for NMR and MRI detection, and also suggest a way to compare the performance of the detectors. The paper also takes a close look at chiplaboratory augmented mMR, and applications within the broad soft matter area. The review aims to contribute to a better understanding of both the scientific potential and the actual limits of mMR tools in the various interdisciplinary soft matter research fields.

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Section: Micro-coils Integrated With Micro-electronicsmentioning

confidence: 99%

Microscale nuclear magnetic resonance: a tool for soft matter research

et al. 2012

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Preliminary study of planar RF coils for Magnetic Resonance Microscopy

Wu¹,

Hsieh²,

Liu³

et al. 2005

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference

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A CMOS microcoil-associated preamplifier for NMR spectroscopy

Cherifi

Abouchi

et al. 2005

IEEE Trans. Circuits Syst. I

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For improving sensitivity of nuclear magnetic resonance (NMR) measurements, an in-field preamplifier in a low-cost CMOS process is presented. It is based on a second-generation positive current conveyor (CCII+), with an impedance-matching output stage. The circuit has been designed with optimization of key performances, such as bandwidth, noise, and offset voltage. There have also been precautions taken against potential effect of strong magnetic field under which the circuit should operate. The designed preamplifier has a voltage gain of 15 dB and a bandwidth of 100 MHz. After fabrication of the circuit, we have carried out testing work, including in-field circuit test and characterization of MOS transistors. Under 2-T magnetic field, there have not been substantial changes in overall circuit performances compared to results obtained by post-layout simulations. For an experiment of NMR measurements with and without in-field preamplifier, the circuit is coupled with a receiver micro-coil. The experiment has been to detect protons at 85.13-MHz resonance frequency under 2-T magnetic field with water sample. The obtained results have shown a 14-dB signal-to-noise ratio improvement when the preamplifier is associated with the receiver coil.Index Terms-Current conveyor, in-field preamplifier, nuclear magnetic resonance (NMR) active probe, receiver micro-coil.

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Development of an integrated detector for NMR microscopy

Cited by 3 publications

References 4 publications

Microscale nuclear magnetic resonance: a tool for soft matter research

Microscale nuclear magnetic resonance: a tool for soft matter research

Preliminary study of planar RF coils for Magnetic Resonance Microscopy

A CMOS microcoil-associated preamplifier for NMR spectroscopy

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