Development of an Inexpensive RGB Color Sensor for the Detection of Hydrogen Cyanide Gas

Greenawald, Lee A.; Boss, Gerry R.; Snyder, Jay L.; Reeder, Aaron; Bell, S. A.

doi:10.1021/acssensors.7b00396

Cited by 36 publications

(24 citation statements)

References 12 publications

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“…Subsequently, the MD was placed upside down, and 1 min later, the resulted chip was recorded with a portable colorimeter (Figure S1) and subjected for further RGB analysis. Data are presented in terms of total color differences (Δ C ) using the Euclidean distance eq , where Δ R , Δ G , and Δ B are the changes in R, G, and B colors from blank values, respectively. The calibration curve for target was generated by the final results.…”

Section: Experimental Sectionmentioning

confidence: 99%

Integrating Target-Triggered Aptamer-Capped HRP@Metal–Organic Frameworks with a Colorimeter Readout for On-Site Sensitive Detection of Antibiotics

et al. 2020

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Colorimetric analytical strategies exhibit great promise in developing on-site detection methods for antibiotics, while substantial recent research efforts remain problematic due to dissatisfactory sensitivity. Taking this into account, we develop a novel colorimetric sensor for in-field detection of antibiotics by using aptamer (Apt)-capped and horseradish peroxidise (HRP)embedded zeolitic metal azolate framework-7 (MAF-7) (Apt/HRP@MAF-7) as target recognition and signal transduction, respectively. With the substrate 3,3′,5,5′-tetramethylbenzidine (TMB)-impregnated chip attached on the lid, the assay can be conveniently operated in a tube and reliably quantified by a handheld colorimeter. Hydrophilic MAF-7 can not only prevent HRP aggregation but also enhance HRP activity, which would benefit its detection sensitivity. Besides, the catalytic activity of HRP@MAF-7 can be sealed through assembling with Apt and controllably released based on the bioresponsivity via forming target-Apt complexes. Consequently, a significant color signal can be observed owing to the oxidation of colorless TMB to its blue-green oxidized form oxTMB. As a proof-of-concept, portable detection of streptomycin was favorably achieved with excellent sensitivity, which is superior to most reported methods and commercial kits. The developed strategy affords a new design pattern for developing on-site antibiotics assays and immensely extends the application of enzyme embedded metal−organic framework composites.

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Section: Experimental Sectionmentioning

confidence: 99%

Integrating Target-Triggered Aptamer-Capped HRP@Metal–Organic Frameworks with a Colorimeter Readout for On-Site Sensitive Detection of Antibiotics

et al. 2020

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“…Although both sensors measured optical absorbance from the indicator dye, the response of the MCbi indicator to HCN (g) differed from the response of the RDI indicator to HF (g) described above because the reaction of MCbi with HCN is reversible. While the equilibrium constant for binding of CN – to monocyanocobinamide is quite large (∼10 8 ), it was previously demonstrated that the back-reaction is observed when HCN vapor is removed from the gas stream . Consistent with its large binding constant, the rate of loss of CN – from the dicyano complex of cobinamide was markedly slower than the rate of binding; thus, substantial time was required for the sensor to recover to its original state (Figure S13, Supporting Information).…”

Section: Resultsmentioning

confidence: 76%

“…While the equilibrium constant for binding of CN − to monocyanocobinamide is quite large (∼10 8 ), 36 it was previously demonstrated that the back-reaction is observed when HCN vapor is removed from the gas stream. 42 Consistent with its large binding constant, the rate of loss of CN − from the dicyano complex of cobinamide was markedly slower than the rate of binding; thus, substantial time was required for the sensor to recover to its original state (Figure S13, Supporting Information).…”

Section: ■ Results and Discussionmentioning

confidence: 91%

Remote Detection of HCN, HF, and Nerve Agent Vapors Based on Self-Referencing, Dye-Impregnated Porous Silicon Photonic Crystals

Vijayakumar

Chaix

et al. 2020

ACS Sens.

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A one-dimensional photonic crystal is prepared from porous silicon (pSi) and impregnated with a chemically specific colorimetric indicator dye to provide a self-referenced vapor sensor for the selective detection of hydrogen fluoride (HF), hydrogen cyanide (HCN), and the chemical nerve agent diisopropyl fluorophosphate (DFP). The photonic crystal is prepared with two stop bands: one that coincides with the optical absorbance of the relevant activated indicator dye and the other in a spectrally “clear” region, to provide a reference. The inner pore walls of the pSi sample are then modified with octadecylsilane to provide a hydrophobic interior, and the indicator dye of interest is then loaded into the mesoporous matrix. Remote analyte detection is achieved by measurement of the intensity ratio of the two stop bands in the white light reflectance spectrum, which provides a means to reliably detect colorimetric changes in the indicator dye. Indicator dyes were chosen for their specificity for the relevant agents: rhodamine-imidazole (RDI) for HF and DFP, and monocyanocobinamide (MCbi) for HCN. The ratiometric readout allows detection of HF and HCN at concentrations (14 and 5 ppm, respectively) that are below their respective IDLH (immediately dangerous to life and health) concentrations (30 ppm for HF; 50 ppm for HCN); detection of DFP at a concentration of 114 ppb is also demonstrated. The approach is insensitive to potential interferents such as ammonia, hydrogen chloride, octane, and the 43-component mixture of VOCs known as EPA TO-14A, and to variations in relative humidity (20–80% RH). Detection of HF and HCN spiked into the complex mixture EPA TO-14A is demonstrated. The approach provides a general means to construct robust remote detection systems for chemical agents.

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“…By monitoring the RGB color change of the light reflected from the paper, hydrogen cyanide gas can be easily detected, which is vitally important to security check. [6] In addition, according to the tri-receptor theory of human color blind to both visible and near infrared light (NIR) illumination (from 500 to 1200 nm). [23] This unique phenomenon is associated with the relatively strong absorption in the UV region, which is reasonable considering the wavelength dependent absorption coefficient and the relatively small thickness of the Si film.…”

Section: Introductionmentioning

confidence: 99%

High‐Accuracy and Broadband Wavelength Sensor with Detection Region Ranging from Deep Ultraviolet to Near Infrared Light

Xiao

et al. 2021

Advanced Optical Materials

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vision, color perception in the human visual system can be predicted by using the color matching curve. Based on this, a high-resolution digital still camera was constructed using a color filter array (CFA) equipped with a charge-coupled device (CCD) to process the recognized objects and reconstruct the color images. [7] Generally, the representative wavelength sensor has been achieved by using a broadband inorganic semiconductor photodiode combined with a dichromatic prism or a set of filters. [8,9] For example, full-color sensing can be easily achieved by employing filter arrays that consist of a periodic arrangement of red, green, and blue filters. [10] This type of sensor is characterized by relatively narrow operation range (e.g., visible light). [11] As an important complement to above filter-assisted wavelength sensors, filterless sensor has lately received increasing research interest as well. [12][13][14] Although this device can quantitatively discriminate the wavelength of incident light, they are however characterized by relatively narrow sensing range and complicated device structures which entail very sophisticated instrument during device fabrication process. [15][16][17][18][19][20] Thereby, high-resolution wavelength sensor with simple device geometry is in great demand.Various study have shown that photodetectors composed of artificial nanostructures in the form of nanofilm or nanowires can exhibit unique optoelectronic characteristics. [21,22] For example, Xu et al. has recently reported that graphene/ thin Si (200 nm) heterojunction can display pronounced photoresponse to UV light illumination (365 nm), but is virtually In this paper, a broadband wavelength sensor which is composed of two horizontally stacked photodetectors is reported. The top part is a monolayer graphene (MLG)/thin Si/MLG heterojunction device and the bottom part is a MLG/Ge Schottky junction device. Owing to the thin thickness of the Si and the wavelength-dependent absorption coefficients of both Si and Ge, the two photodetectors exhibit sharp contrast in photon-generation rate when illuminated with different wavelengths of light. This distinction in photon generation leads to completely different evolution in photocurrent, and the corresponding relationship between the photocurrent ratio and wavelength can be easily expressed as a monotonic function, via which the wavelength in a broad range from deep ultraviolet (265 nm) to near infrared light (1550 nm) can be easily calculated. Notably, the average relative error and the average absolute error of the wavelength sensor are estimated to be 2.1% and 2.3 nm, respectively, which are much better than previously reported values.

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Development of an Inexpensive RGB Color Sensor for the Detection of Hydrogen Cyanide Gas

Cited by 36 publications

References 12 publications

Integrating Target-Triggered Aptamer-Capped HRP@Metal–Organic Frameworks with a Colorimeter Readout for On-Site Sensitive Detection of Antibiotics

Integrating Target-Triggered Aptamer-Capped HRP@Metal–Organic Frameworks with a Colorimeter Readout for On-Site Sensitive Detection of Antibiotics

Remote Detection of HCN, HF, and Nerve Agent Vapors Based on Self-Referencing, Dye-Impregnated Porous Silicon Photonic Crystals

High‐Accuracy and Broadband Wavelength Sensor with Detection Region Ranging from Deep Ultraviolet to Near Infrared Light

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