Development of an improved colonization system for human-derived <i>Bifidobacterium longum</i> subsp. <i>longum</i> in conventional mice through the feeding of raffinose or 1-kestose
Mina SHIMADA,
Youhei KAWASE,
Kei SONOYAMA
et al.
Abstract:How bifidobacteria colonize and survive in the intestine is not fully understood. The
administration of bifidobacteria to conventional mice can be used to evaluate their
ability to colonize the intestine in the presence of endogenous gut microbiota. However,
human-derived bifidobacteria do not readily colonize the intestines of conventional mice,
and although colonization by
Bifidobacterium breve
UCC2003 has been
achieved, the viability of such populations requires improvement. Therefore… Show more
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